贾氏分期是 Dukes' B 期结直肠癌“根治性”切除术后预后的一个预测指标。
Jass staging is a predictor of outcome following "curative" resection of Dukes' B colorectal carcinoma.
作者信息
Mander B J, Carney L J, Scott H J, Donaldson D R
机构信息
Department of Surgery, St Peter's Hospital, Surrey, UK.
出版信息
Surgeon. 2006 Aug;4(4):227-30. doi: 10.1016/s1479-666x(06)80064-8.
BACKGROUND AND AIMS
We have sought to determine if the addition of the Jass pathological classification to Dukes' staging would provide improved prognostic information for patients undergoing curative surgery for Dukes' B colorectal carcinoma.
PATIENTS AND METHODS
One hundred and eighty three patients who underwent curative surgery for Dukes' B colorectal cancers between December 1988 and January 1998 were identified. An assessment of Jass scoring was made at the time of initial histological staging. All patients entered a comprehensive follow-up system.
RESULTS
Jass grouping was found to correlate significantly with cancer specific mortality rates; group III having a worse prognosis than groups I and II (p<0.005). There was no significant difference between either local recurrence or systemic recurrence and the Jass group.
CONCLUSION
The Jass classification provides additional prognostic information in patients following curative resection of Dukes' B colorectal carcinoma and may therefore facilitate the selection of patients who will benefit most from adjuvant treatment
背景与目的
我们试图确定在Dukes分期基础上增加Jass病理分类是否能为接受根治性手术的Dukes B期结直肠癌患者提供更优的预后信息。
患者与方法
确定了1988年12月至1998年1月期间接受Dukes B期结直肠癌根治性手术的183例患者。在初始组织学分期时进行Jass评分评估。所有患者均进入全面的随访系统。
结果
发现Jass分组与癌症特异性死亡率显著相关；III组预后比I组和II组差（p<0.005）。局部复发或全身复发与Jass组之间无显著差异。
结论
Jass分类为接受Dukes B期结直肠癌根治性切除术后的患者提供了额外的预后信息，因此可能有助于选择最能从辅助治疗中获益的患者。
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