Borbély A A, Huston J P, Waser P G
Brain Res. 1975 Sep 12;95(1):89-101. doi: 10.1016/0006-8993(75)90209-7.
The effects of 60-60 min light-dark (LD) cycles on sleep, feeding, drinking and motor activity were investigated in the rat. Waking, consummatory behaviour and motor activity were inhibited by light, while sleep was enhanced. The effects were dependent on the intensity of light. The percentage of slow wave sleep (SS) increased within the first 15 min of the light period and reached a plateau within 30 min. The reduction of SS during darkness showed a similar time-course. The percentage of paradoxical sleep (PS) started to increase only 15 min after the onset of light and continued to rise during the first 15 min of darkness. All parameters exhibited a free-running circadian rhythm. The LD-induced changes of SS were largest during the circadian phase in which the animal was active. The changes of PS which succeeded the onset or offset of light, were largest in the inactive circadian phase. The most immediate influence of changes in illumination is exerted on the slow wave component of sleep. Hypotheses to account for the temporary dissociation between the two sleep states are discussed.
研究了60-60分钟明暗（LD）循环对大鼠睡眠、进食、饮水和运动活动的影响。清醒、进食行为和运动活动受光照抑制，而睡眠则增强。这些影响取决于光照强度。慢波睡眠（SS）百分比在光照期的前15分钟内增加，并在30分钟内达到平稳状态。黑暗期间SS的减少呈现出类似的时间进程。异相睡眠（PS）百分比仅在光照开始后15分钟开始增加，并在黑暗的前15分钟内持续上升。所有参数均表现出自由运行的昼夜节律。LD诱导的SS变化在动物活跃的昼夜节律阶段最大。光照开始或结束后PS的变化在不活跃的昼夜节律阶段最大。光照变化的最直接影响作用于睡眠的慢波成分。讨论了解释两种睡眠状态之间暂时分离的假说。
