Harris Anthony D, McGregor Jessina C, Furuno Jon P
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Clin Infect Dis. 2006 Sep 1;43 Suppl 2:S57-61. doi: 10.1086/504479.
Multidrug-resistant gram-negative bacteria are an emerging problem. The present article addresses 2 relevant questions: (1) should active surveillance be performed to identify patients colonized with multidrug-resistant gram-negative bacteria, and (2) should contact isolation precautions be taken with patients colonized or infected with multidrug-resistant gram-negative bacteria? Data and variables that are needed to scientifically answer these questions are reviewed, as are existing data on Pseudomonas aeruginosa, Enterobacteriaceae (Escherichia coli and Klebsiella species in particular), and Acinetobacter baumannii.
多重耐药革兰氏阴性菌是一个新出现的问题。本文探讨两个相关问题：（1）是否应进行主动监测以识别携带多重耐药革兰氏阴性菌的患者，以及（2）对于携带或感染多重耐药革兰氏阴性菌的患者是否应采取接触隔离预防措施？文中回顾了科学回答这些问题所需的数据和变量，以及关于铜绿假单胞菌、肠杆菌科（特别是大肠杆菌和克雷伯菌属）和鲍曼不动杆菌的现有数据。
