用于毛细管电色谱的整体式对映体选择性固定相。

Monolithic enantiomer-selective stationary phases for capillary electrochromatography.

作者信息

Qin Feng, Xie Chuanhui, Yu Zhiyuan, Kong Liang, Ye Mingliang, Zou Hanfa

机构信息

National Chromatographic Research & Analysis Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.

出版信息

J Sep Sci. 2006 Jul;29(10):1332-43. doi: 10.1002/jssc.200600030.

DOI:10.1002/jssc.200600030

PMID:16894777

Abstract

Monolithic materials have become a well-established format for stationary phases in the field of capillary electrochromatography. Four types of monoliths, namely particle-fixed, silica-based, polymer-based, and molecularly imprinted monoliths, have been utilized as enantiomer-selective stationary phases in CEC. This review summarizes recent developments in the area of monolithic enantiomer-selective stationary phases for CEC. The preparative procedure and the characterization of these columns are highlighted. In addition, the disadvantages and limitations of different monolithic enantiomer-selective stationary phases in CEC are briefly discussed.

摘要

整体材料已成为毛细管电色谱领域固定相的一种成熟形式。四种类型的整体柱，即颗粒固定型、硅胶基型、聚合物基型和分子印迹整体柱，已被用作毛细管电色谱中的对映体选择性固定相。本文综述了毛细管电色谱整体对映体选择性固定相领域的最新进展。重点介绍了这些色谱柱的制备方法和表征。此外，还简要讨论了不同整体对映体选择性固定相在毛细管电色谱中的缺点和局限性。