Mora-Brambila Ana Bertha, Trujillo-Hernández Benjamín, Coll-Cardenas Rafael, Huerta Miguel, Trujillo Xóchitl, Vásquez Clemente, Olmedo-Buenrostro Bertha Alicia, Millan-Guerrero Rebeca O, Elizalde Alejandro
Facultad de Enfermería, Universidad de Colima, Colima, México.
Lepr Rev. 2006 Jun;77(2):114-20.
Peripheral nerve lesions are the most important cause of disability in leprosy patients. Electrophysiological studies are used in the diagnosis and prognosis of neuropathy. Nerve conduction is the most frequently used electrophysiological test method to detect neuropathy, although it evaluates only a part of the peripheral nervous system. Blink reflex and H-reflex are electrophysiological tests which evaluate facial and trigeminal nerve function. This study determined the frequencies of blink reflex, H-reflex and motor and sensory nerve conduction alterations in twenty five heterogeneous, clinic patients with lepromatous leprosy and a control group of 20 healthy subjects. Study results showed a decrease in motor and sensory nerve conduction in 40% and 30%, respectively. In blink reflex (BR), right R1 was altered in latency in 20% of patients, left R1 in 20%, right ipsilateral R2 in 16%, left ipsilateral R2 in 20%, and right and left contralateral R2 were altered in 32% of patients. There was an absence of H-reflex in 16% (n = 4) and prolonged latency in 4% (n = 1).
周围神经病变是麻风患者致残的最重要原因。电生理研究用于神经病变的诊断和预后评估。神经传导是检测神经病变最常用的电生理测试方法，尽管它仅评估外周神经系统的一部分。眨眼反射和H反射是评估面神经和三叉神经功能的电生理测试。本研究确定了25例不同类型的瘤型麻风临床患者以及20名健康对照者的眨眼反射、H反射以及运动和感觉神经传导改变的发生率。研究结果显示，运动和感觉神经传导分别有40%和30%出现下降。在眨眼反射（BR）中，20%的患者右侧R1潜伏期改变，20%的患者左侧R1潜伏期改变，16%的患者右侧同侧R2潜伏期改变，16%的患者左侧同侧R2潜伏期改变，32%的患者右侧和左侧对侧R2潜伏期改变。16%（n = 4）的患者H反射消失，4%（n = 1）的患者潜伏期延长。
