Dissemond Joachim, Körber Andreas, Grabbe Stephan
Universitätsklinikum Essen, Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie.
J Dtsch Dermatol Ges. 2006 Aug;4(8):627-34. doi: 10.1111/j.1610-0387.2006.06052.x.
In Germany about 0.7% of the adult population have a chronic leg ulcer. Although chronic venous insufficiency accounts for at least 80% of all chronic leg ulcers, knowledge of the relevant differential diagnostic considerations is of crucial importance, in particular for patients who are refractory to therapy. In addition to vascular disease, other causes include neuropathic, metabolic, hematologic and exogenous factors as well as neoplasias, infections, drugs, genetic defects and some primary skin disorders. For the long-term successful treatment of patients with chronic leg ulcers, it is necessary to identify all relevant factors, in order to enable a pathogenesis-oriented, interdisciplinary therapeutic approach.
在德国，约0.7%的成年人口患有慢性腿部溃疡。尽管慢性静脉功能不全至少占所有慢性腿部溃疡的80%，但了解相关的鉴别诊断要点至关重要，特别是对于治疗难治的患者。除血管疾病外，其他病因包括神经性、代谢性、血液学和外源性因素以及肿瘤、感染、药物、基因缺陷和一些原发性皮肤病。为了长期成功治疗慢性腿部溃疡患者，有必要识别所有相关因素，以便采取以发病机制为导向的跨学科治疗方法。
