Prisant L Michael, Gujral Jaspal S, Mulloy Anthony L
Hypertension and Clinical Pharmacology Unit, Medical College of Georgia, Augusta, GA 30912-3104, USA.
J Clin Hypertens (Greenwich). 2006 Aug;8(8):596-9. doi: 10.1111/j.1524-6175.2006.05180.x.
Isolated systolic hypertension is the most common form of hypertension, especially among patients 50 years or older. What is not appreciated is that there are secondary causes of isolated systolic hypertension. Hyperthyroidism increases systolic blood pressure by decreasing systemic vascular resistance, increasing heart rate, and raising cardiac output. Potential cardiovascular consequences of hyperthyroidism include atrial arrhythmias (especially atrial fibrillation), pulmonary hypertension, left ventricular hypertrophy, and heart failure. The prevalence of hypertension is greater among hyperthyroid patients than euthyroid patients. Whether there is a blunted nocturnal decline in ambulatory blood pressure among hyperthyroid patients is more controversial. Treatment is associated with a reduction in systolic blood pressure, heart rate, and cardiac output.
单纯收缩期高血压是最常见的高血压形式，在50岁及以上患者中尤为常见。人们尚未认识到的是，单纯收缩期高血压存在继发性病因。甲状腺功能亢进通过降低体循环血管阻力、增加心率和提高心输出量来升高收缩压。甲状腺功能亢进的潜在心血管后果包括房性心律失常（尤其是心房颤动）、肺动脉高压、左心室肥厚和心力衰竭。甲状腺功能亢进患者的高血压患病率高于甲状腺功能正常的患者。甲状腺功能亢进患者动态血压夜间下降是否减弱更具争议性。治疗可使收缩压、心率和心输出量降低。
