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[激光及后装放疗对结肠肿瘤的姑息治疗]

[Palliative treatment of colonic tumors with laser and afterloading irradiation].

作者信息

Semler P

机构信息

I. Innere Abteilung, Wenckebach-Krankenhaus, Berlin.

出版信息

Dtsch Med Wochenschr. 1990 Mar 2;115(9):328-31. doi: 10.1055/s-2008-1065010.

Abstract

Laser photoablation was undertaken in 46 patients (27 women and 19 men, mean age 81 [66-93] years) with malignant tumours of the colon, either for tumour bleeding (n = 7) or stenosis (n = 39), and in 27 patients combined with afterloading 192Ir irradiation. Operation had been refused by 14 patients, 22 were primarily inoperable, one received preoperative radiotherapy for ileus. The radiotherapy was inadequate in only one patient who had to be operated on for subileus. Eleven patients have had a mean survival time of 13.5 months, 22 died after a mean of 7.5 months. No patient died from ileus or any other complication of the palliative tumour treatment. These results suggest that combined laser and afterloading irradiation is an alternative treatment of malignant tumour of the lower intestinal tract or for patients who decline surgical treatment.

摘要

对46例(27例女性和19例男性,平均年龄81[66 - 93]岁)患有结肠恶性肿瘤的患者进行了激光光凝治疗,治疗原因要么是肿瘤出血(n = 7),要么是狭窄(n = 39),其中27例患者还联合了192铱后装放疗。14例患者拒绝手术,22例最初无法手术,1例因肠梗阻接受了术前放疗。仅1例因不完全性肠梗阻而必须接受手术的患者放疗效果不佳。11例患者的平均生存时间为13.5个月,22例患者平均7.5个月后死亡。没有患者死于肠梗阻或姑息性肿瘤治疗的任何其他并发症。这些结果表明,激光联合后装放疗是治疗下消化道恶性肿瘤或拒绝手术治疗患者的一种替代治疗方法。

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