[使用高剂量率铱-192后装装置对气管支气管肿瘤进行腔内照射]
[Endoluminal irradiation of tracheobronchial tumors using a high dose rate iridium-192 afterloading device].
作者信息
Schedel H, Rohloff R, Huber R M, Duft S, Kantlehner R
机构信息
Radiologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München.
出版信息
Strahlenther Onkol. 1988 Apr;164(4):202-7.
We report about 50 patients with inoperable bronchus tumors treated since March 1986 in a prospective non randomized study with high dose rate iridium-192 afterloading (AL) irradiation in 140 applications. 26 patients were treated combined with external irradiation. 32 were treated before with laser therapy, one with chemotherapy (small cell carcinoma). The actuarial survival rate (Kaplan-Meier) was 26% after 36 weeks for all patients; 38% for combined endoluminal and external irradiation and 9% for patients treated with AL alone. Death was caused by the local tumor in 85%. In 41% lethal bleeding was seen.
我们报告了自1986年3月以来接受治疗的约50例无法手术的支气管肿瘤患者，这是一项前瞻性非随机研究，采用高剂量率铱-192后装（AL）放疗，共进行了140次照射。26例患者接受了外照射联合治疗。32例患者之前接受过激光治疗，1例接受过化疗（小细胞癌）。所有患者36周后的精算生存率（Kaplan-Meier法）为26%；腔内照射与外照射联合治疗的患者为38%，仅接受AL治疗的患者为9%。85%的患者死于局部肿瘤。41%的患者出现致命性出血。
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