Pakisch B, Kohek P, Stücklschweiger G, Smolle-Jüttner F G, Poier E, Fall A, Leitner H, Friehs G, Hackl A
Universitätsklinik für Radiologie, Abteilung für Thorax- und Hyperbare Chirurgie, Graz.
Strahlenther Onkol. 1990 Apr;166(4):247-50.
From 1/87 to 12/88, 20 patients with anatomically or functionally inoperable carcinomas of the esophagus (cT1-3/N0-2/M0-1) were treated by endoluminal Ir-192 HDR brachytherapy (1-3 sessions, each 5-7 Gy) and percutaneous irradiation (50-70 Gy/2 Gy). In 10 cases a bouginage or combined dilatation and retrograde Nd-Yag-laser debulking was done before irradiation. The response of the treatment was documented by endoscopy (degree of stenoses) and symptoms (dysphagia score according to De Meester). In 95% of all cases the degree of stenoses was diminished and an improvement of dysphagia was found in 100%. The mean duration of oral uptake of properly chewed food could be prolonged to 308 days.
从1987年1月至1988年12月，对20例解剖学或功能上无法手术切除的食管癌患者（cT1 - 3/N0 - 2/M0 - 1）进行了腔内铱 - 192高剂量率近距离放疗（1 - 3次，每次5 - 7 Gy）和经皮照射（50 - 70 Gy/2 Gy）。10例患者在放疗前进行了探条扩张或联合扩张及逆行钕 - 钇铝石榴石激光减瘤。通过内镜检查（狭窄程度）和症状（根据De Meester的吞咽困难评分）记录治疗反应。在所有病例中，95%的狭窄程度减轻，100%的患者吞咽困难得到改善。正常咀嚼食物的经口摄入平均持续时间可延长至308天。
