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不同治疗计划系统与直线加速器组合的调强放射治疗(IMRT):问题及检测方法

Intensity-modulated radiation therapy (IMRT) with different combinations of treatment-planning systems and linacs: issues and how to detect them.

作者信息

Dobler Barbara, Lorenz Friedlieb, Wertz Hansjörg, Polednik Martin, Wolff Dirk, Steil Volker, Lohr Frank, Wenz Frederik

机构信息

Department of Radiation Oncology, Mannheim Medical Center, University of Heidelberg, Mannheim, Germany.

出版信息

Strahlenther Onkol. 2006 Aug;182(8):481-8. doi: 10.1007/s00066-006-1544-6.

Abstract

PURPOSE

To compare different combinations of intensity-modulated radiation therapy (IMRT) system components with regard to quality assurance (QA), especially robustness against malfunctions and dosimetry.

MATERIAL AND METHODS

Three different treatment-planning systems (TPS), two types of linacs and three multileaf collimator (MLC) types were compared: commissioning procedures were performed for the combination of the TPS Corvus 5.0 (Nomos) and KonRad v2.1.3 (Siemens OCS) with the linacs KD2 (Siemens) and Synergy (Elekta). For PrecisePLAN 2.03 (Elekta) measurements were performed for Elekta Synergy only. As record and verify (R&V) system Multi-Access v7 (IMPAC) was used. The use of the serial tomotherapy system Peacock (Nomos) was investigated in combination with the Siemens KD2 linac.

RESULTS

In the comparison of calculated to measured dose, problems were encountered for the combination of KonRad and Elekta MLC as well as for the Peacock system. Multi-Access failed to assign the collimator angle correctly for plans with multiple collimator angles per beam. Communication problems of Multi-Access with both linacs were observed, resulting in incorrect recording of the treatment. All reported issues were addressed by the manufacturers.

CONCLUSION

For the commissioning of IMRT systems, the whole chain from the TPS to the linac has to be investigated. Components that passed the commissioning in another clinical environment can have severe malfunctions when used in a new environment. Therefore, not only single components but the whole chain from planning to delivery has to be evaluated in commissioning and checked regularly for QA.

摘要

目的

比较调强放射治疗(IMRT)系统组件的不同组合在质量保证(QA)方面的情况,尤其是对故障的稳健性和剂量测定。

材料与方法

比较了三种不同的治疗计划系统(TPS)、两种直线加速器类型和三种多叶准直器(MLC)类型:对TPS Corvus 5.0(Nomos)和KonRad v2.1.3(西门子OCS)与直线加速器KD2(西门子)和Synergy(医科达)的组合进行了调试程序。对于PrecisePLAN 2.03(医科达),仅对医科达Synergy进行了测量。使用Multi-Access v7(IMPAC)作为记录与验证(R&V)系统。研究了串行断层放射治疗系统Peacock(Nomos)与西门子KD2直线加速器的组合使用情况。

结果

在计算剂量与测量剂量的比较中,KonRad和医科达MLC的组合以及Peacock系统出现了问题。对于每束具有多个准直器角度的计划,Multi-Access未能正确分配准直器角度。观察到Multi-Access与两种直线加速器之间存在通信问题,导致治疗记录错误。所有报告的问题均由制造商解决。

结论

对于IMRT系统的调试,必须研究从TPS到直线加速器的整个链条。在另一个临床环境中通过调试的组件在新环境中使用时可能会出现严重故障。因此,在调试中不仅要评估单个组件,还要评估从计划到交付的整个链条,并定期进行QA检查。

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