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在胆囊床放置浸有0.5%布比卡因的外科用氧化纤维素对腹腔镜胆囊切除术后的疼痛有效。

Placement of 0.5% bupivacaine-soaked Surgicel in the gallbladder bed is effective for pain after laparoscopic cholecystectomy.

作者信息

Verma G R, Lyngdoh T S, Kaman L, Bala I

机构信息

Department of Surgery and Anesthesia, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Surg Endosc. 2006 Oct;20(10):1560-4. doi: 10.1007/s00464-005-0284-5. Epub 2006 Aug 1.

DOI:10.1007/s00464-005-0284-5
PMID:16897291
Abstract

BACKGROUND

This study aimed to determine the character of pain after laparoscopic cholecystectomy and its relief with 0.5% bupivacaine-soaked Surgicel placed in the gallbladder bed.

METHODS

For this study, 60 patients with chronic cholecystitis were divided into four groups of 15 each: group A (bupivacaine-soaked Surgicel kept in gallbladder bed), group B (bupivacaine infiltrated at trocar sites), group C (bupivacaine infiltrated into the gallbladder bed and at trocar sites, and group D (normal saline in the gallbladder bed and at trocar sites). Postoperatively, the character of pain was noted, and its relief was assessed with visual analog scale (VAS) scoring.

RESULTS

The findings showed that 78.33% of the patients had visceral pain, 70% experienced parietal, and 23.33% reported shoulder pain after laparoscopic cholecystectomy. The visceral pain was significantly less in the group A patients than in the control subjects (p < 0.05), and none of them experienced shoulder pain. The mean VAS score at 4, 8, and, 24 h in the group A patients also was less than in control group D: 26.37 +/- 16.24 versus 38.30 +/- 9.51, 23.23 +/- 14.28 versus 33.73 +/- 7.96, and 18.36 +/- 13.00 versus 28.60 +/- 9.42, respectively. Trocar-site infiltration alone was not effective in relieving the parietal pain.

CONCLUSION

Visceral pain is prominent after laparoscopic cholecystectomy and can be effectively controlled by 0.5% bupivacaine-soaked Surgicel in the gallbladder bed alone. Trocar-site infiltration alone is ineffective.

摘要

背景

本研究旨在确定腹腔镜胆囊切除术后疼痛的特点,以及通过在胆囊床放置浸有0.5%布比卡因的外科用可吸收止血纱布来缓解疼痛的效果。

方法

在本研究中,60例慢性胆囊炎患者被分为四组,每组15例:A组(在胆囊床放置浸有布比卡因的外科用可吸收止血纱布)、B组(在穿刺孔部位注射布比卡因)、C组(在胆囊床和穿刺孔部位注射布比卡因)、D组(在胆囊床和穿刺孔部位注入生理盐水)。术后,记录疼痛特点,并采用视觉模拟评分法(VAS)评估疼痛缓解情况。

结果

研究结果显示,78.33%的患者有内脏痛,70%有腹壁痛,23.33%的患者在腹腔镜胆囊切除术后出现肩部疼痛。A组患者的内脏痛明显少于对照组(p<0.05),且无一例出现肩部疼痛。A组患者在术后4小时、8小时和24小时的平均VAS评分也低于对照组D组:分别为26.37±16.24 对 38.30±9.51、23.23±14.28 对 33.73±7.96、18.36±13.00 对 28.60±9.42。单独在穿刺孔部位注射药物对缓解腹壁痛无效。

结论

腹腔镜胆囊切除术后内脏痛较为突出,单独在胆囊床放置浸有0.5%布比卡因的外科用可吸收止血纱布可有效控制。单独在穿刺孔部位注射药物无效。

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Surg Laparosc Endosc. 1998 Dec;8(6):416-20.
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