Castillo-Garza Gerardo, Díaz-Elizondo José A, Cuello-García Carlos A, Villegas-Cabello Oscar
General Surgery, Tecnologico de Monterrey-Escuela de Medicina y Ciencias de la Salud. Postgraduate Area, Monterrey, N. L. México.
JSLS. 2012 Jan-Mar;16(1):105-11. doi: 10.4293/108680812X13291597716221.
The aim of this study was to evaluate the effect of bupivacaine irrigated at the surgical bed on postoperative pain relief in laparoscopic cholecystectomy patients.
This study included 60 patients undergoing elective laparoscopic cholecystectomy who were prospectively randomized into 2 groups. The placebo group (n=30) received 20cc saline without bupivacaine, installed into the gallbladder bed. The bupivacaine group (n=30) received 20cc of 0.5% bupivacaine in at the same surgical site. Pain was assessed at 0, 6, 12, and 24 hours by using a visual analog scale (VAS).
A significant difference (P=.018) was observed in pain levels between both groups at 6 hours postoperatively. The average analgesic requirement was lower in the bupivacaine group, but this did not reach statistical significance.
In our study, the use of bupivacaine irrigated over the surgical bed was an effective method for reducing pain during the first postoperative hours after laparoscopic cholecystectomy.
本研究旨在评估在手术床处冲洗布比卡因对腹腔镜胆囊切除术患者术后疼痛缓解的效果。
本研究纳入60例行择期腹腔镜胆囊切除术的患者，将其前瞻性随机分为2组。安慰剂组（n = 30）在胆囊床处注入20cc不含布比卡因的生理盐水。布比卡因组（n = 30）在相同手术部位注入20cc 0.5%布比卡因。使用视觉模拟评分法（VAS）在术后0、6、12和24小时评估疼痛程度。
术后6小时两组疼痛程度存在显著差异（P = 0.018）。布比卡因组的平均镇痛需求较低，但未达到统计学意义。
在我们的研究中，在手术床处冲洗布比卡因是腹腔镜胆囊切除术后最初几个小时减轻疼痛的有效方法。
