Yagui M, Perales M T, Asencios L, Vergara L, Suarez C, Yale G, Salazar C, Saavedra M, Shin S, Ferrousier O, Cegielski P
Instituto Nacional de Salud, Lima, Perú.
Int J Tuberc Lung Dis. 2006 Aug;10(8):838-43.
Timely diagnosis and effective, safe treatment are essential to reduce transmission and improve outcomes for patients with tuberculosis. Aside from laboratory methods, many programmatic factors influence the overall turnaround time (TAT) in diagnosing multidrug-resistant tuberculosis (MDR-TB). We measured each step in the overall TAT required for MDR-TB in two of five health districts of Lima, Peru. The total TAT, from initial sputum specimen to diagnosis and appropriate treatment, was 5 months, almost twice as long as the bacteriological procedures per se. Expensive investments in laboratory technology may yield low returns unless the programmatic aspects of the diagnostic process are streamlined at the same time.
及时诊断以及有效、安全的治疗对于减少结核病传播和改善患者预后至关重要。除实验室方法外，许多规划因素会影响耐多药结核病（MDR-TB）诊断的总体周转时间（TAT）。我们在秘鲁利马五个卫生区中的两个区测量了耐多药结核病总体周转时间中的每一步。从最初的痰标本到诊断及适当治疗的总周转时间为5个月，几乎是细菌学检查本身所需时间的两倍。除非同时简化诊断过程的规划方面，否则对实验室技术的昂贵投资可能回报率较低。
