[肾病综合征患儿泌尿系统畸形的发生率]

[Incidence of urinary system malformations in children with the nephrotic syndrome].

作者信息

Borzecka Halina, Wieczorkiewicz-Płaza Anna, Sikora Przemysław, Bieniaś Beata, Majewski Marek, Kołłataj Barbara, Zajaczkowska Małgorzata

机构信息

Klinika Nefrologii Dzieciecej, Akademii Medycznej w Lublinie.

出版信息

Przegl Lek. 2006;63 Suppl 3:211-3.

PMID:16898533

Abstract

The purposes of the study were a) to assess the incidence of urinary system malformations in children with the nephrotic syndrome (NS) and b) to estimate their effect on clinical course of the NS. A retrospective analysis comprised medical records of patients aged 2-18 years hospitalized in the Department of Pediatric Nephrology, University Children's Hospital, Lublin. Urinary tract infections (UTI) occurred in 28% of children with the NS. Imaging evaluation revealed urinary system malformations in 21.2% of children with the NS and UTI. Urinary system malformations constituted 5.9% of all children hospitalized because of the NS. Urinary system malformations included vesico-ureteral reflux (42.8%), renal duplication (28.6%), renal agenesis (14.3%) and diverticulum of the bladder (14.3%). In 48% of children with the NS and urinary system malformations, frequent recurrences of the syndrome were observed.

摘要

该研究的目的是

a）评估肾病综合征（NS）患儿泌尿系统畸形的发生率；b）评估这些畸形对NS临床病程的影响。一项回顾性分析纳入了在卢布林大学儿童医院儿科肾脏病科住院的2至18岁患者的病历。28%的NS患儿发生了尿路感染（UTI）。影像学评估显示，21.2%的NS合并UTI患儿存在泌尿系统畸形。泌尿系统畸形占因NS住院的所有患儿的5.9%。泌尿系统畸形包括膀胱输尿管反流（42.8%）、重复肾（28.6%）、肾缺如（14.3%）和膀胱憩室（14.3%）。在48%的NS合并泌尿系统畸形患儿中，观察到该综合征频繁复发。