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1
Pathologic observations in human allograft recipients treated with FK 506.接受FK 506治疗的人类同种异体移植受者的病理观察
Transplant Proc. 1990 Feb;22(1):25-34.
2
Conversion from cyclosporine to FK 506 in liver allograft recipients with cyclosporine-related complications.肝移植受者中因环孢素相关并发症而从环孢素转换为FK506治疗。
Transplant Proc. 1990 Feb;22(1):6-12.
3
Histopathology of human renal allograft rejection under FK 506: a comparison with cyclosporine.FK506 治疗下人肾移植排斥反应的组织病理学：与环孢素的比较。
Transplant Proc. 1991 Feb;23(1 Pt 2):944-6.
4
Conversion of liver allograft recipients from cyclosporine to FK 506-based immunosuppression: benefits and pitfalls.肝移植受者从环孢素转换为基于FK 506的免疫抑制：益处与风险。
Transplant Proc. 1991 Feb;23(1 Pt 1):14-21.
5
Adult heart transplantation under tacrolimus (FK506) immunosuppression: histopathologic observations and comparison to a cyclosporine-based regimen with lympholytic (ATG) induction.他克莫司（FK506）免疫抑制下的成人心脏移植：组织病理学观察及与基于环孢素并采用淋巴细胞溶解剂（抗胸腺细胞球蛋白）诱导方案的比较
J Heart Lung Transplant. 1997 Jul;16(7):723-34.
6
Chronic allograft rejection.慢性移植物排斥反应。
Immunol Rev. 1993 Aug;134:33-81. doi: 10.1111/j.1600-065x.1993.tb00639.x.
7
Gastrointestinal and metabolic problems associated with immunosuppression with either CyA or FK 506 in liver transplantation.肝移植中与使用环孢素A（CyA）或他克莫司（FK 506）进行免疫抑制相关的胃肠道和代谢问题。
Transplant Proc. 1990 Feb;22(1):37-40.
8
Acute rejection and heart infection rates in FK 506- versus cyclosporine A-treated heart transplant recipients: an endomyocardial biopsy pathologic study.FK506与环孢素A治疗的心脏移植受者的急性排斥反应和心脏感染率：一项心内膜心肌活检病理研究
J Heart Lung Transplant. 1997 Sep;16(9):982-4.
9
Liver, kidney, and thoracic organ transplantation under FK 506.在使用FK506情况下的肝脏、肾脏及胸部器官移植。
Ann Surg. 1990 Sep;212(3):295-305; discussion 306-7. doi: 10.1097/00000658-199009000-00008.
10
The effects of FK 506 on renal function after liver transplantation.FK506对肝移植后肾功能的影响。
Transplant Proc. 1990 Feb;22(1):17-20.

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Protective effect of silymarin on tacrolimus-induced kidney and liver toxicity.水飞蓟素对他克莫司诱导的肝肾毒性的保护作用。
BMC Complement Med Ther. 2022 Dec 13;22(1):331. doi: 10.1186/s12906-022-03803-x.
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Clinicopathologic Characteristics of Centrilobular Injury in Pediatric Liver Transplantation.小儿肝移植中中央小叶损伤的临床病理特征。
Liver Transpl. 2021 Feb;27(3):416-424. doi: 10.1002/lt.25958. Epub 2020 Dec 31.
3
FKBP Ligands-Where We Are and Where to Go?FKBP配体——我们所处的位置与前进的方向？
Front Pharmacol. 2018 Dec 5;9:1425. doi: 10.3389/fphar.2018.01425. eCollection 2018.
4
Chronic liver allograft rejection in a population treated primarily with tacrolimus as baseline immunosuppression: long-term follow-up and evaluation of features for histopathological staging.在以他克莫司作为基础免疫抑制进行主要治疗的人群中慢性肝移植排斥反应：长期随访及组织病理学分期特征评估
Transplantation. 2000 Jun 15;69(11):2330-6. doi: 10.1097/00007890-200006150-00019.
5
Chronic rejection. A general overview of histopathology and pathophysiology with emphasis on liver, heart and intestinal allografts.慢性排斥反应。组织病理学和病理生理学概述，重点关注肝、心脏和肠道同种异体移植。
Ann Transplant. 1997;2(2):27-44.
6
Adult heart transplantation under tacrolimus (FK506) immunosuppression: histopathologic observations and comparison to a cyclosporine-based regimen with lympholytic (ATG) induction.他克莫司（FK506）免疫抑制下的成人心脏移植：组织病理学观察及与基于环孢素并采用淋巴细胞溶解剂（抗胸腺细胞球蛋白）诱导方案的比较
J Heart Lung Transplant. 1997 Jul;16(7):723-34.
7
Kidney transplantation in highly sensitized patients: reappraisal of etiology, evaluation, and management protocols.高度致敏患者的肾移植：病因、评估及管理方案的重新评估
World J Urol. 1996;14(4):206-17. doi: 10.1007/BF00182069.
8
Microvascular changes in renal allografts associated with FK506 (Tacrolimus) therapy.与FK506（他克莫司）治疗相关的肾移植微血管变化。
Am J Surg Pathol. 1996 Mar;20(3):306-12. doi: 10.1097/00000478-199603000-00007.
9
FK506 (tacrolimus), a novel immunosuppressant in organ transplantation: clinical, biomedical, and analytical aspects.FK506（他克莫司），一种器官移植中的新型免疫抑制剂：临床、生物医学及分析方面
Clin Chem. 1993 Nov;39(11 Pt 1):2219-28.
10
The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine.接受FK506治疗的肾移植受者中与同种异体移植排斥反应及药物毒性相关的组织病理学变化。临床意义及与环孢素的比较。
Am J Surg Pathol. 1993 Jan;17(1):60-8. doi: 10.1097/00000478-199301000-00007.

本文引用的文献

1
Orthotopic liver transplantation: a pathological study of 63 serial liver biopsies from 17 patients with special reference to the diagnostic features and natural history of rejection.原位肝移植：对17例患者的63次连续肝脏活检进行病理研究，特别关注排斥反应的诊断特征和自然病程。
Hepatology. 1984 Nov-Dec;4(6):1212-22. doi: 10.1002/hep.1840040620.
2
Biopsy-directed immunosuppression following hepatic transplantation in man.人体肝移植后活检指导下的免疫抑制治疗。
Transplantation. 1985 Jun;39(6):589-96. doi: 10.1097/00007890-198506000-00003.
3
Blood and graft eosinophilia as predictors of rejection in human liver transplantation.血液和移植物嗜酸性粒细胞增多作为人类肝移植排斥反应的预测指标。
Transplantation. 1989 Jan;47(1):72-4. doi: 10.1097/00007890-198901000-00016.
4
Role of dopaminergic and adrenergic receptors in the pathogenesis of arterial lesions induced by fenoldopam mesylate and dopamine in the rat.多巴胺能和肾上腺素能受体在甲磺酸非诺多泮和多巴胺诱导的大鼠动脉病变发病机制中的作用。
Am J Pathol. 1989 Aug;135(2):339-49.
5
Renal transplantation in baboons under FK 506.在使用FK506的情况下狒狒的肾移植
Surgery. 1989 Aug;106(2):444-50; discussion 450-1.
6
Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs.FK506与环孢素联合治疗对犬同种异体肾移植受者存活时间及血管变化的影响
Transplantation. 1989 Aug;48(2):193-7. doi: 10.1097/00007890-198908000-00003.
7
Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction.FK506对犬、猴和狒狒同种异体移植物的免疫抑制作用：特别提及与其他药物的协同作用及耐受性诱导。
Surgery. 1988 Aug;104(2):239-49.
8
Prolongation of skin allograft survival in rats by a novel immunosuppressive agent, FK506.新型免疫抑制剂FK506延长大鼠同种异体皮肤移植存活时间
Transplantation. 1988 Jan;45(1):206-9. doi: 10.1097/00007890-198801000-00042.
9
Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats.
Transplantation. 1987 Dec;44(6):734-8. doi: 10.1097/00007890-198712000-00002.
10
Studies of the effects of FK506 on renal allografting in the beagle dog.FK506对比格犬同种异体肾移植影响的研究。
Transplantation. 1987 Dec;44(6):729-33. doi: 10.1097/00007890-198712000-00001.

Pathologic observations in human allograft recipients treated with FK 506.

作者信息

Demetris A J, Fung J J, Todo S, Banner B, Zerbe T, Sysyn G, Starzl T E

机构信息

Departments of Surgery, University of Pittsburgh, PA.

出版信息

Transplant Proc. 1990 Feb;22(1):25-34.

PMID:1689891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2903856/
Abstract
摘要