Baptista P M, Mercadante M T, Macedo E C, Schwartzman J S
Development Disorders Program, Mackenzie Presbyterian University, São Paulo, Brazil.
J Intellect Disabil Res. 2006 Sep;50(Pt 9):662-6. doi: 10.1111/j.1365-2788.2006.00818.x.
Rett syndrome (RS) is a pervasive developmental disorder with cognitive and neuromotor impairments (including loss of handiness and loss of communicative skills).
To verify whether girls with RS use their gaze intentionally, by observing their performance in three cognitive tasks: (1) verbal instruction condition (look at picture X), (2) recognition and matching of pictures (look at the one that is the same), and (3) categorization of pictures (look at the one that is similar).
Seven girls diagnosed with RS according to DSM-IV criteria were studied. Eyegaze technology was used to record the girls' eye movements' responses to visual stimulation.
The comparison of fixation time on the alternatives revealed a higher percentage (62.4%) of correct alternatives (chi(2) = 76.31; P = 0.000). Of the seven children assessed, only one did not present predominance of fixations on the correct alternatives in any one of the tasks. One did well in all tasks. Six responded correctly to all verbal instructions.
The rate of correct answers suggests that there is measurable and intentional gaze in RS girls and it can be used as a path to explore their cognitive performance.
雷特综合征（RS）是一种广泛性发育障碍，伴有认知和神经运动障碍（包括手部灵巧性丧失和沟通技能丧失）。
通过观察7名患有雷特综合征的女孩在三项认知任务中的表现，验证她们是否有意使用目光注视：（1）言语指令条件（看图片X），（2）图片识别与匹配（看相同的那张），以及（3）图片分类（看相似的那张）。
对7名根据《精神疾病诊断与统计手册》第四版（DSM-IV）标准诊断为雷特综合征的女孩进行研究。使用眼动追踪技术记录女孩们对视觉刺激的眼动反应。
对备选图片注视时间的比较显示，正确备选图片的注视比例更高（62.4%）（χ² = 76.31；P = 0.000）。在评估的7名儿童中，只有1名在任何一项任务中都没有表现出对正确备选图片的注视优势。1名在所有任务中表现良好。6名对所有言语指令都做出了正确反应。
正确答案的比例表明，雷特综合征女孩存在可测量的有意注视，并且可以将其作为探索她们认知表现的途径。
