Brouwer J, Nagelkerke D, De Jongste M J, Boute W, Den Heijer P, Lie K I
Department of Cardiology, University Hospital Groningen, The Netherlands.
Pacing Clin Electrophysiol. 1990 Mar;13(3):302-13. doi: 10.1111/j.1540-8159.1990.tb02044.x.
In a retrospective study we analyzed the unipolar endocardial evoked response signal (ERS) of 103 patients prior to pacemaker implantation. The objective of this study was to give a complete description of the ERS morphology and to evaluate influences on this morphology of both various electrode characteristics and pacing rate. In addition, spontaneous endocardial signals were studied. The results demonstrate that acute leads had both higher R wave and T wave amplitudes and a faster downslope of the T wave. In the acute leads those with porous titanium carbon coated tips showed a more pronounced T wave. Pacing rate influences the R wave amplitude and the stimulus to T wave interval. Both stimulus to maximum and stimulus to minimum T wave interval show an exponential correlation with the stimulus interval. The interval between maximum and minimum of the T wave and the absolute amplitude of T wave are not influenced by rate. Although there were significant correlations of the spontaneous endocardial signal with the ERS, the predictive value of the spontaneous signal for the ERS morphology is low. Prospective studies will be necessary to confirm the findings in this study.
在一项回顾性研究中,我们分析了103例起搏器植入术前患者的单极心内膜诱发反应信号(ERS)。本研究的目的是全面描述ERS形态,并评估各种电极特性和起搏频率对该形态的影响。此外,还研究了自发心内膜信号。结果表明,急性导线的R波和T波振幅更高,T波下降斜率更快。在急性导线中,带有多孔钛碳涂层尖端的导线T波更明显。起搏频率影响R波振幅以及刺激到T波间期。刺激到最大T波间期和刺激到最小T波间期均与刺激间期呈指数相关。T波最大和最小之间的间期以及T波的绝对振幅不受频率影响。虽然自发心内膜信号与ERS存在显著相关性,但自发信号对ERS形态的预测价值较低。需要进行前瞻性研究来证实本研究中的发现。