Boute W, Cals G L, Den Heijer P, Wittkampf F H
Vitatron Medical, Dieren, The Netherlands.
Pacing Clin Electrophysiol. 1988 Nov;11(11 Pt 2):1693-7. doi: 10.1111/j.1540-8159.1988.tb06297.x.
Recently developed stimulation techniques are capable of eliminating polarization afterpotentials caused by the emitted stimulus. A well-controlled study method was developed to initiate various degrees of fusion and to monitor changes in the morphology of the endocardial signal. The study was performed on two dogs. The zone during which fusion could be provoked was less than 30 ms in both dogs. In addition, the results show a significant decrease in the endocardial T-wave amplitude as soon as fusion was noticed, while the QT interval then slightly lengthened. Furthermore, the evoked R-wave duration shortened during fusion, while the stimulus to R-wave interval lengthened. These results have consequences for pacemakers that use evoked endocardial signal characteristics for driving a pacemaker function.
最近开发的刺激技术能够消除由发射的刺激引起的极化后电位。开发了一种控制良好的研究方法来引发不同程度的融合,并监测心内膜信号形态的变化。该研究在两只狗身上进行。两只狗中能够引发融合的时间段均小于30毫秒。此外,结果显示,一旦注意到融合,心内膜T波振幅就会显著降低,而QT间期随后会略有延长。此外,在融合过程中诱发的R波持续时间缩短,而刺激到R波的间期延长。这些结果对利用诱发的心内膜信号特征来驱动起搏器功能的起搏器有影响。