Zorn Kevin C, Orvieto Marcelo A, Mikhail Albert A, Lotan Tamara, Gerber Glenn S, Shalhav Arieh L, Steinberg Gary D
Section of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637, USA.
Urology. 2006 Aug;68(2):428.e5-7. doi: 10.1016/j.urology.2006.03.012.
Metachronous presentation of metastatic renal cell carcinoma (RCC) to the ureter is extremely rare. We report a solitary metachronous metastatic RCC in the contralateral ureter 14 months after right radical nephrectomy for Fuhrman grade 2 pT3a clear cell disease after the patient re-presented with gross hematuria. The proximal left ureteral lesion was excised followed by ileal-ureteral interposition. Pathologic examination confirmed metastatic RCC. To date, only 51 cases of metastatic RCC to the ureter have been reported, with only 6 occurring metachronously in the contralateral ureter. Also, we report the presence of focal extramedullary hematopoiesis occurring within this metastatic lesion.
转移性肾细胞癌(RCC)异时性转移至输尿管极为罕见。我们报告1例在因Fuhrman 2级pT3a透明细胞癌行右侧根治性肾切除术后14个月,对侧输尿管出现孤立性异时性转移性RCC的病例,该患者再次出现肉眼血尿。切除了左侧输尿管近端病变,随后行回肠-输尿管间置术。病理检查证实为转移性RCC。迄今为止,仅报告了51例RCC转移至输尿管的病例,其中仅6例为对侧输尿管异时性转移。此外,我们报告了在该转移性病变内存在局灶性髓外造血。