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病例报告：前列腺中的髓外造血

Case Report: Extramedullary Hematopoiesis in the Prostate.

作者信息

Fisher Lucas A B, Baniak Nicholas

机构信息

Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.

出版信息

Int J Surg Pathol. 2025 May;33(3):757-760. doi: 10.1177/10668969241283742. Epub 2024 Oct 3.

DOI:10.1177/10668969241283742
PMID:39360392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12006670/
Abstract

Extramedullary hematopoiesis is the physiological process of hematopoiesis occurring outside of the bone marrow and is an extremely rare occurrence in the prostate, with only 1 previously documented report in the English literature. We present a specimen from a 56-year-old man who was found to have a palpable nodule on digital rectal examination and visible findings on ultrasound, confirmed to be extramedullary hematopoiesis on the prostate core.

摘要

髓外造血是指在骨髓以外发生的造血生理过程，在前列腺中极为罕见，英文文献中此前仅有1例报道。我们展示了一份来自一名56岁男性的标本，该患者在直肠指检时发现可触及结节，超声检查有可见表现，经前列腺穿刺活检证实为髓外造血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b15/12006670/40ad283637eb/10.1177_10668969241283742-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b15/12006670/39d8bbb70728/10.1177_10668969241283742-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b15/12006670/352eae727c05/10.1177_10668969241283742-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b15/12006670/40ad283637eb/10.1177_10668969241283742-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b15/12006670/39d8bbb70728/10.1177_10668969241283742-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b15/12006670/352eae727c05/10.1177_10668969241283742-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b15/12006670/40ad283637eb/10.1177_10668969241283742-fig3.jpg

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本文引用的文献

1
Renal Extramedullary Hematopoiesis in Mast Cell Leukemia with Bone Marrow Fibrosis.伴有骨髓纤维化的肥大细胞白血病中的肾外髓外造血
Case Rep Hematol. 2024 Jan 3;2024:3502887. doi: 10.1155/2024/3502887. eCollection 2024.
2
Extramedullary haematopoiesis in renal neoplasms.
Histopathology. 2024 May;84(6):1070-1072. doi: 10.1111/his.15138. Epub 2024 Jan 8.
3
Extramedullary Hematopoiesis: A Forgotten Diagnosis and a Great Mimicker of Malignancy.髓外造血：一个被遗忘的诊断及恶性肿瘤的强大模仿者。
J Comput Assist Tomogr. 2023;47(3):445-452. doi: 10.1097/RCT.0000000000001428. Epub 2023 Jan 14.
4
Extramedullary hematopoiesis in the absence of myeloproliferative neoplasm: Mayo Clinic case series of 309 patients.无骨髓增殖性肿瘤情况下的髓外造血：梅奥诊所309例患者病例系列
Blood Cancer J. 2018 Nov 19;8(12):119. doi: 10.1038/s41408-018-0156-6.
5
Extramedullary hematopoiesis secondary to malignant solid tumors: a case report and literature review.恶性实体瘤继发的髓外造血：一例病例报告及文献复习
Cancer Manag Res. 2018 Jun 8;10:1461-1470. doi: 10.2147/CMAR.S161746. eCollection 2018.
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Extramedullary haematopoiesis in the kidney.肾脏中的髓外造血
Clin Kidney J. 2012 Apr;5(2):143-145. doi: 10.1093/ckj/sfs015.
7
Membranous Nephropathy and Intrarenal Extramedullary Hematopoiesis in a Patient With Myelofibrosis.骨髓纤维化患者的膜性肾病和肾内髓外造血
Am J Kidney Dis. 2017 Dec;70(6):874-877. doi: 10.1053/j.ajkd.2017.06.022. Epub 2017 Aug 16.
8
Extramedullary hematopoiesis: Elucidating the function of the hematopoietic stem cell niche (Review).髓外造血：阐明造血干细胞微环境的功能（综述）
Mol Med Rep. 2016 Jan;13(1):587-91. doi: 10.3892/mmr.2015.4621. Epub 2015 Nov 27.
9
Renal extramedullary hematopoiesis: interstitial and glomerular pathology.肾外髓造血：间质及肾小球病变
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10
Extra-medullary haematopoiesis: a pictorial review of its typical and atypical locations.髓外造血：其典型和非典型部位的影像学综述
J Med Imaging Radiat Oncol. 2012 Oct;56(5):538-44. doi: 10.1111/j.1754-9485.2012.02397.x. Epub 2012 Jun 25.