Bennett R L, Blanks R G
Cancer Screening Evaluation Unit, Section of Epidemiology, Institute of Cancer Research, Cotswold Road, Sutton, Surrey SM2 5NG, UK.
Breast. 2007 Feb;16(1):55-9. doi: 10.1016/j.breast.2006.05.008. Epub 2006 Aug 14.
The UK NHSBSP defines standards for both cancer detection rate and recall rate for assessment but has not explicitly set a defined standard for positive predictive value (PPV) of recall. However, as PPV is defined as the percentage of women who are recalled and have a final diagnosis of cancer, a standard for PPV is an implicit consequence of the standards for cancer detection rate and recall rate. The standards are defined in terms of a lower level of acceptability known as the 'minimum standard' and a higher level of acceptability referred to as the 'target'. The target can be shown to be a PPV of more than 5.1% for prevalent screens and more than 8.4% for incident screens. This paper will explore the role of PPV as a performance measure and show how making moderate increases in PPV for programmes with the lowest PPVs could lead to major improvements in the overall efficiency of the programme.
英国国民医疗服务体系乳房筛查项目(NHSBSP)为癌症检出率和召回评估率制定了标准,但尚未明确设定召回阳性预测值(PPV)的既定标准。然而,由于PPV被定义为被召回且最终诊断为癌症的女性所占的百分比,PPV标准是癌症检出率和召回率标准的一个隐含结果。这些标准是根据较低的可接受水平(称为“最低标准”)和较高的可接受水平(称为“目标”)来定义的。对于现患筛查,目标PPV可达到5.1%以上;对于新发病例筛查,目标PPV可达到8.4%以上。本文将探讨PPV作为一项绩效指标的作用,并展示对于PPV最低的项目,适度提高PPV如何能大幅提升项目的整体效率。