Division of Cancer and Stem Cells, University of Nottingham, School of Medicine, City Hospital Campus, Hucknall Road, Nottingham NG5 1PB, England (Y.C.); Nottingham Breast Institute, Nottingham University Hospitals NHS Trust, Nottingham, England (J.J.J.); Department of Radiology, Cheltenham General Hospital, Cheltenham, England (E.J.C.); and Young Person and Adult Screening Programmes, Public Health England, Sheffield, England (J.J.).
Radiol Imaging Cancer. 2020 Sep 25;2(5):e200016. doi: 10.1148/rycan.2020200016. eCollection 2020 Sep.
To compare an individual's Personal Performance in Mammographic Screening (PERFORMS) score with their Breast Screening Information System (BSIS) real-life performance data and determine which parameters in the PERFORMS scheme offer the best reflection of BSIS real-life performance metrics.
In this retrospective study, the BSIS real-life performance metrics of individual readers ( = 452) in the National Health Service Breast Screening Program (NHSBSP) in England were compared with performance in the test set-based assessment scheme over a 3-year period from 2013 to 2016. Cancer detection rate (CDR), recall rate, and positive predictive value (PPV) were calculated for each reader, for both real-life screening and the PERFORMS test. For each metric, real-life and test set versions were compared using a Pearson correlation. The real-life CDR, recall rate, and PPV of outliers were compared against other readers (nonoutliers) using analysis of variance.
BSIS real-life CDRs, recall rates, and PPVs showed positive correlations with the equivalent PERFORMS measures ( < .001, = .002, and < .001, respectively). The mean real-life CDR of PERFORMS outliers was 7.2 per 1000 women screened and was significantly lower than other readers (nonoutliers) where the real-life CDR was 7.9 ( = .002). The mean real-life screening PPV of PERFORMS outliers was 0.14% and was significantly lower than the nonoutlier group who had a mean PPV of 0.17% ( = .006).
The use of test set-based assessment schemes in a breast screening program has the potential to predict and identify poor performance in real life.© RSNA, 2020 Breast, ScreeningSee also the commentary by Thigpen and Rapelyea in this issue.
将个人在乳房 X 线摄影筛查中的表现评分(PERFORMS)与他们的乳房筛查信息系统(BSIS)实际表现数据进行比较,并确定 PERFORMS 方案中的哪些参数能够最好地反映 BSIS 实际表现指标。
在这项回顾性研究中,比较了英格兰国家卫生服务乳房筛查计划(NHSBSP)中个体读者的 BSIS 实际表现指标(n=452)与 2013 年至 2016 年 3 年间基于测试集的评估方案中的表现。为每位读者计算了真实筛选和 PERFORMS 测试的癌症检出率(CDR)、召回率和阳性预测值(PPV)。对于每个指标,使用 Pearson 相关系数比较真实和测试集版本。使用方差分析比较离群值的真实 CDR、召回率和 PPV 与其他读者(非离群值)的差异。
BSIS 真实 CDR、召回率和 PPV 与等效 PERFORMS 测量值呈正相关(均<.001,=.002 和 <.001)。PERFORMS 离群值的真实平均 CDR 为每 1000 名筛查妇女 7.2 例,明显低于其他读者(非离群值),其真实 CDR 为 7.9(=.002)。PERFORMS 离群值的真实筛查 PPV 平均值为 0.14%,明显低于非离群值组,后者的平均 PPV 为 0.17%(=.006)。
在乳房筛查计划中使用基于测试集的评估方案有可能预测和识别实际表现不佳的情况。