• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[有选择性指征的小肾肿瘤保留肾单位手术的长期结果]

[Long-term results of nephron-sparing surgery for small renal tumors with elective indications].

作者信息

Pertiia A R, Managadze L G

出版信息

Georgian Med News. 2006 Jun(135):12-6.

PMID:16905798
Abstract

The widespread use of modern radiological techniques substantially changed clinical presentation of renal cell carcinoma (RCC) in the recent decades. Currently, more than one half of all patients with surgically resectable renal tumors are detected incidentally. In this due interest in nephron sparing surgery (NSS) for the treatment of small localized tumors has increased. The amount of healthy parenchyma that should be removed together with the tumor to minimize the risk of local recurrence is an important and controversial issue. In the present study we retrospectively studied 44 cases of NSS performed for elective indications. A total of 44 patients underwent elective NSS from 1994 to 2001. According to the operative techniques the patients were distributed in two groups. Group I consisted of 17 patients who underwent "enucleoresection" with a small part of normal parenchyma around the excised tumors. The rest 27 patients (Group II) underwent NSS by means of enucleation. Mean follow-up was 88.36+/-24.75 months (range: 49-146 months). The mean tumor size was 37,04+/-4,65 cc (range: 25 to 45). There was no perioperative mortality. Hemorrhage was observed in 1 patient (5,9%) from Group I. Urinary leakage was observed in 3 (6,8%) cases in both groups: two (11,7%) in group I and one (3,7%) in group II. No local recurrence was observed during the follow-up period. One patient (2, 8%) developed distant metastases and died at 81 month postoperatively. 5-year cancer specific survival was 97,6 %. Simple tumor enucleation is a safe and acceptable approach for elective NSS. It provides excellent long-term progression-free and cancer specific survival rates, and is not associated with an increased risk of local recurrence compared with partial nephrectomy.

摘要

近几十年来,现代放射技术的广泛应用极大地改变了肾细胞癌(RCC)的临床表现。目前,超过一半的可手术切除肾肿瘤患者是偶然发现的。因此,对保留肾单位手术(NSS)治疗小的局限性肿瘤的兴趣增加。为将局部复发风险降至最低,应与肿瘤一并切除的健康实质组织量是一个重要且有争议的问题。在本研究中,我们回顾性研究了44例因选择性指征而行NSS的病例。1994年至2001年,共有44例患者接受了选择性NSS。根据手术技术,患者分为两组。第一组由17例患者组成,他们接受了“剜除切除术”,切除肿瘤周围一小部分正常实质组织。其余27例患者(第二组)通过剜除术接受了NSS。平均随访时间为88.36±24.75个月(范围:49 - 146个月)。平均肿瘤大小为37.04±4.65立方厘米(范围:25至45)。无围手术期死亡。第一组有1例患者(5.9%)出现出血。两组均有3例(6.8%)出现尿漏:第一组2例(11.7%),第二组1例(3.7%)。随访期间未观察到局部复发。1例患者(2.8%)发生远处转移,术后81个月死亡。5年癌症特异性生存率为97.6%。单纯肿瘤剜除术是选择性NSS的一种安全且可接受的方法。它提供了优异的长期无进展生存率和癌症特异性生存率,与部分肾切除术相比,局部复发风险并未增加。

相似文献

1
[Long-term results of nephron-sparing surgery for small renal tumors with elective indications].[有选择性指征的小肾肿瘤保留肾单位手术的长期结果]
Georgian Med News. 2006 Jun(135):12-6.
2
Progression and long-term survival after simple enucleation for the elective treatment of renal cell carcinoma: experience in 107 patients.单纯眼球摘除术择期治疗肾细胞癌后的进展与长期生存:107例患者的经验
J Urol. 2005 Jul;174(1):57-60; discussion 60. doi: 10.1097/01.ju.0000162019.45820.53.
3
Elective nephron sparing surgery should become standard treatment for small unilateral renal cell carcinoma: Long-term survival data of 216 patients.选择性保留肾单位手术应成为小的单侧肾细胞癌的标准治疗方法:216例患者的长期生存数据。
Eur Urol. 2006 Feb;49(2):308-13. doi: 10.1016/j.eururo.2005.10.020. Epub 2005 Dec 9.
4
Nephron sparing surgery for central renal tumors: experience with 33 cases.肾肿瘤保留肾单位手术治疗中央型肾肿瘤:33例经验
J Urol. 2000 Mar;163(3):737-43.
5
Simple enucleation for the treatment of renal cell carcinoma between 4 and 7 cm in greatest dimension: progression and long-term survival.最大直径在4至7厘米之间的肾细胞癌的单纯剜除术治疗:进展与长期生存情况
J Urol. 2006 Jun;175(6):2022-6; discussion 2026. doi: 10.1016/S0022-5347(06)00275-8.
6
Open partial nephrectomy for imperative and elective indications comparison of peri-operative data and long-term follow-up.因紧急和择期指征行开放性部分肾切除术:围手术期数据及长期随访比较
Scand J Urol Nephrol. 2007;41(6):496-500. doi: 10.1080/00365590701485970.
7
Outcome of nephron-sparing surgery for T1b renal cell carcinoma.T1b期肾细胞癌保留肾单位手术的疗效
BJU Int. 2009 May;103(10):1344-8. doi: 10.1111/j.1464-410X.2008.08230.x. Epub 2008 Nov 25.
8
[Long-term outcomes of mini-margin nephron sparing surgery for renal cell carcinoma].[小切缘保留肾单位手术治疗肾细胞癌的长期疗效]
Zhonghua Wai Ke Za Zhi. 2008 Feb 15;46(4):286-8.
9
Nephron-sparing surgery for renal cell carcinoma in the solitary kidney.对孤立肾肾细胞癌行保留肾单位手术。
Scand J Urol Nephrol. 2007;41(1):10-3. doi: 10.1080/00365590600911225.
10
Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy.对于4至7厘米之间适当选择的肾细胞癌,保留肾单位手术的结果与根治性肾切除术相似。
J Urol. 2004 Mar;171(3):1066-70. doi: 10.1097/01.ju.0000113274.40885.db.

引用本文的文献

1
Tumor enucleation for the treatment of T1 renal tumors: A systematic review and meta-analysis.肿瘤剜除术治疗 T1 期肾肿瘤:系统评价和荟萃分析。
Investig Clin Urol. 2022 Mar;63(2):126-139. doi: 10.4111/icu.20210361.