Laurell H, Hansson L-E, Gunnarsson U
Department of Surgery, Mora Hospital, Mora, Sweden.
Gerontology. 2006;52(6):339-44. doi: 10.1159/000094982. Epub 2006 Aug 11.
Diagnosis of acute abdominal pain in older persons is a challenge, with the age-related increase in concurrent diseases. In most western countries the number of elderly people is constantly rising, which means that an increasing proportion of patients admitted for abdominal pain at the emergency department are elderly.
To characterize differences in clinical presentation and diagnostic accuracy between younger and more elderly patients with acute abdominal pain.
Patients admitted to Mora Hospital with abdominal pain of up to seven days' duration were registered according to a detailed schedule. From 1st February 1997 to 1st June 2000, 557 patients aged 65-79 years and 274 patients aged > or = 80 years were registered. Patients aged 20-64 years (n = 1,458) served as a control group.
A specific diagnosis, i.e. other than 'nonspecific abdominal pain', was established in 76 and 78% of the patients aged 65-79 and > or = 80 years respectively, and in 64% of those aged 20-64 (p < 0.001). Pain duration before admission increased with age (p < 0.003), as did frequency and duration of hospitalization (p < 0.0001). Hospital stay increased from 170 days per 100 emergency admissions in the control group to 320 and 458 days in the younger and older study groups, respectively. At the emergency department, older patients were more often misdiagnosed than control patients (52 vs. 45%; p = 0.002). At discharge the diagnosis was more accurate in the control group (86 vs. 77%; p < 0.0001). Hospital mortality was higher among older patients (23/831 vs. 2/1,458; p < 0.001). The admission-to-surgery interval was increased (1.8 vs. 0.9 days, p < 0.0001) in patients > or = 65 years. Rebound tenderness (p < 0.0001), local rigidity (p = 0.003) and rectal tenderness (p = 0.004) were less common in the older than in the control patients with peritonitis. In patients > or = 65 years, C-reactive protein did not differ between patients operated on and those not, contrary to the finding in patients < 65 years (p < 0.0001).
Both the preliminary diagnosis at the emergency department and the discharge diagnosis were less reliable in elderly than in younger patients. Elderly patients more often had specific organic disease and arrived at the emergency department after a longer history of abdominal pain compared to younger patients.
由于老年人并发疾病随年龄增长而增多,因此对老年人急性腹痛进行诊断颇具挑战性。在大多数西方国家,老年人数量持续上升,这意味着在急诊科因腹痛入院的患者中,老年患者的比例日益增加。
描述年轻和年长急性腹痛患者在临床表现和诊断准确性方面的差异。
按照详细的时间表,对入住莫拉医院、腹痛持续时间长达7天的患者进行登记。在1997年2月1日至2000年6月1日期间,登记了557名年龄在65 - 79岁的患者和274名年龄≥80岁的患者。年龄在20 - 64岁的患者(n = 1458)作为对照组。
年龄在65 - 79岁和≥80岁的患者中,分别有76%和78%确诊为特定疾病,即非“非特异性腹痛”,而年龄在20 - 64岁的患者中这一比例为64%(p < 0.001)。入院前疼痛持续时间随年龄增长而增加(p < 0.003),住院频率和住院时间也是如此(p < 0.0001)。住院时间从对照组每100例急诊入院患者的170天,分别增加到年轻研究组的320天和年长研究组的458天。在急诊科,老年患者比对照组患者更常被误诊(52%对45%;p = 0.002)。出院时,对照组的诊断更准确(86%对77%;p < 0.0001)。老年患者的医院死亡率更高(23/831对2/1458;p < 0.001)。65岁及以上患者从入院到手术的间隔时间增加(1.8天对0.9天,p < 0.0001)。与对照组患有腹膜炎的患者相比,老年患者的反跳痛(p < 0.0001)、局部肌紧张(p = 0.003)和直肠触痛(p = 0.004)较少见。在65岁及以上的患者中,接受手术和未接受手术的患者C反应蛋白无差异,这与65岁以下患者的情况相反(p < 0.0001)。
与年轻患者相比,老年患者在急诊科的初步诊断和出院诊断都不太可靠。与年轻患者相比,老年患者更常患有特定的器质性疾病,且腹痛病史更长才到急诊科就诊。