Sharma Sanjeev, Turcotte Robert E, Isler Marc H, Wong Cindy
Orthopaedic Oncology Unit, McGill University Health Centre, 1650 Cedar Avenue, Montreal, Quebec, Canada.
Clin Orthop Relat Res. 2006 Sep;450:28-32. doi: 10.1097/01.blo.0000229316.66501.fc.
We retrospectively ascertained the outcomes and complications with a cemented rotating hinge implant. Implant failure was defined as amputation of the affected limb and revision of part or all of the components. We included 77 consecutive distal femoral replacements performed between 1989 and 2004. The mean age was 42 years (range, 12-87 years) and the mean length of followup was 52 months (range, 1.5-157 months). Five-year implant survival was 84% and 10-year survival was 79%. There were 67 bone sarcomas, two soft tissue sarcomas and eight metastatic carcinomas. At followup, 54 patients had no evidence of disease, 16 were alive with disease, and seven were dead from disease. Six patients had deep infection, two of which required amputations. There were five local recurrences; three needed amputation and two soft-tissue excisions only. Three patients sustained a tibial bearing fracture and one required replacement of loose bumper. No revision was performed for stem loosening, stem fracture, or bushing wear. Musculoskeletal Tumor Society 1987 scores averaged 30 and Toronto Extremity Salvage Scores averaged 77.6 at latest followup. Cemented endoprosthesis is a reliable procedure after resection of the distal femur for tumors.
Therapeutic study, level IV (case series).
我们回顾性地确定了使用骨水泥固定旋转铰链型植入物的治疗结果及并发症。植入物失败定义为患侧肢体截肢以及部分或全部组件翻修。我们纳入了1989年至2004年间连续进行的77例股骨远端置换术。平均年龄为42岁(范围12 - 87岁),平均随访时间为52个月(范围1.5 - 157个月)。植入物5年生存率为84%,10年生存率为79%。其中有67例骨肉瘤、2例软组织肉瘤和8例转移性癌。随访时,54例患者无疾病证据,16例带瘤生存,7例因疾病死亡。6例发生深部感染,其中2例需要截肢。有5例局部复发;3例需要截肢,2例仅行软组织切除。3例患者发生胫骨承重骨折,1例需要更换松动的缓冲器。未因柄松动、柄骨折或衬套磨损而进行翻修。在最近一次随访时,肌肉骨骼肿瘤学会1987年评分平均为30分,多伦多肢体挽救评分平均为77.6分。对于股骨远端肿瘤切除术后,骨水泥固定假体是一种可靠的手术方法。
治疗性研究,IV级(病例系列)。