Marculescu Camelia E, Berbari Elie F, Cockerill Franklin R, Osmon Douglas R
Medical University of South Carolina, Charleston, SC, USA.
Clin Orthop Relat Res. 2006 Oct;451:55-63. doi: 10.1097/01.blo.0000229317.43631.81.
The association of certain microorganisms, such as Staphylococcus epidermidis, Staphylococcus aureus, and beta-hemolytic streptococci, with prosthetic joint infection (PJI) has been recognized for many years. To our knowledge, a systematic review of the presentation and management of less commonly encountered species of coagulase-negative staphylococci, nutritional-variant streptococci, aerobic non-spore and spore forming Gram-positive or anaerobic bacteria is not available. We therefore sought to provide a comprehensive literature review of PJI due to these microorganisms that will provide a valuable and quick reference for clinicians caring for these patients. We conducted a Medline search of all case reports and case series of PJI due to unusual aerobic and anaerobic bacteria. The presentation, surgical, and medical management strategies were reviewed. Appropriate medical and surgical management of such infections is complex and evolving as newer diagnostic tests, surgical techniques and antimicrobials become available. Management of patients with these infections requires close collaboration between the orthopaedic surgeon, infectious disease specialist and microbiology laboratory.
某些微生物，如表皮葡萄球菌、金黄色葡萄球菌和β溶血性链球菌与人工关节感染（PJI）的关联已被认识多年。据我们所知，目前尚无关于凝固酶阴性葡萄球菌、营养变异型链球菌、需氧非芽孢和芽孢形成革兰氏阳性菌或厌氧菌等较少见菌种引起的人工关节感染的表现及管理的系统综述。因此，我们试图对这些微生物引起的人工关节感染进行全面的文献综述，为照料这些患者的临床医生提供有价值且快速的参考。我们对所有因不常见需氧菌和厌氧菌引起的人工关节感染的病例报告和病例系列进行了Medline检索。对其表现、手术及药物管理策略进行了综述。随着更新的诊断测试、手术技术和抗菌药物的出现，此类感染的适当药物和手术管理很复杂且不断发展。对这些感染患者的管理需要骨科医生、传染病专家和微生物实验室之间密切合作。
