Menendez Lawrence R, Ahlmann Elke R, Kermani Cyrus, Gotha Heather
Department of Orthopaedics, Keck School of Medicine, Los Angeles County-University of Southern California Medical Center, 1200 N. State Street, Los Angeles, CA 90033, USA.
Clin Orthop Relat Res. 2006 Sep;450:46-51. doi: 10.1097/01.blo.0000229332.91158.05.
Limb salvage has become an important alternative to amputation in the treatment of bone neoplasms. We sought to determine whether the survivorship of modular proximal femur endoprostheses compares to that of custom implants and if specified factors predict failure. We additionally assessed the intermediate clinical and functional results with regard to complications and outcome. We retrospectively reviewed 96 consecutive patients who underwent endoprosthetic reconstruction for neoplastic disease and assessed patient, implant, and limb survivorship. The mean patient age was 59 years (range, 14-86 years). The average duration of followup was 18.1 months (range, 1-129 months). Nine (9.3%) prostheses failed and the rate of revision was 7.3% (7/96). Overall implant survival was 82% at 5 years and 10 years. Survivorship of the limb was 99% at 5 years. Patients in whom the articulating head segment was a total hip had a higher rate of revision compared with those who had undergone bipolar replacement. The mean MSTS score was 22 points (range, 15-25 points). Modular endoprosthetic replacement of the proximal femur is a durable reconstructive option and implants will generally outlive the patient with neoplastic disease. Bipolar head segments should be used whenever possible because of increased survival and decreased rates of dislocation.
Therapeutic study, level IV (case series).
保肢已成为治疗骨肿瘤时截肢的重要替代方法。我们试图确定模块化近端股骨假体的生存率与定制植入物相比如何,以及特定因素是否可预测失败情况。我们还评估了关于并发症和结果的中期临床及功能结果。我们回顾性分析了96例因肿瘤性疾病接受假体重建的连续患者,并评估了患者、植入物及肢体的生存率。患者平均年龄为59岁(范围14 - 86岁)。平均随访时间为18.1个月(范围1 - 129个月)。9个(9.3%)假体失败,翻修率为7.3%(7/96)。5年和10年时总体植入物生存率分别为82%。5年时肢体生存率为99%。与接受双极置换的患者相比,关节头段为全髋关节的患者翻修率更高。平均肌肉骨骼肿瘤学会(MSTS)评分为22分(范围15 - 25分)。近端股骨模块化假体置换是一种持久的重建选择,植入物通常比患有肿瘤性疾病的患者存活时间更长。由于生存率提高和脱位率降低,应尽可能使用双极头段。
治疗性研究,IV级(病例系列)。