Lou Shu-Jie, Liu Jin-Yan, Yang Ruo-Yu, Chen Pei-Jie
Department of Exercise and Sports Science, Shanghai University of Sport, Shanghai, China.
Sheng Li Xue Bao. 2006 Aug 25;58(4):365-9.
To investigate the effect of treadmill running on the ability of learning in young rats, male Sprague-Dawley rats (5 weeks of age) were used for the experiment. Animals were randomly divided into the control and running groups (n=15 in each group). The rats in running group were made run on a motor-driven treadmill for 1 week at a speed of 2 m/min for the first 5 min, at a speed of 5 m/min for the next 5 min, then at a speed of 8 m/min for the last 20 min. Then the Morris water maze was used to observe learning and memory ability of rats in both groups. The tests consisted of place navigation and spatial probe test. We found that, in place navigation training, the latency of rats in running group was less than that in control group (P<0.05); and from the third training session on, there was significant difference between the rats in control and running groups in swimming velocity (P<0.01); furthermore, it was observed that the rats in running group had stronger motivation and more exact orientation in searching for platform, which could be indicated by the index of turn angle and angular velocity. In spatial probe test, there was no significant difference between the two groups in swimming velocity, percentage of swimming distance and frequency of crossing platform in D quadrant, where the platform situated (P>0.05). These findings suggest that low speed treadmill running can enhance the ability of learning in young rats.
为研究跑步机跑步对幼鼠学习能力的影响，选用雄性斯普拉格-道利大鼠（5周龄）进行实验。动物被随机分为对照组和跑步组（每组n = 15）。跑步组的大鼠在电动跑步机上跑步1周，最初5分钟速度为2米/分钟，接下来5分钟速度为5米/分钟，最后20分钟速度为8米/分钟。然后使用莫里斯水迷宫观察两组大鼠的学习和记忆能力。测试包括位置导航和空间探索测试。我们发现，在位置导航训练中，跑步组大鼠的潜伏期短于对照组（P<0.05）；从第三次训练课开始，对照组和跑步组大鼠在游泳速度上存在显著差异（P<0.01）；此外，观察到跑步组大鼠在寻找平台时有更强的动机和更精确的方向，这可以通过转弯角度和角速度指标来表明。在空间探索测试中，两组在游泳速度、游泳距离百分比以及在平台所在的D象限穿越平台的频率方面没有显著差异（P>0.05）。这些发现表明，低速跑步机跑步可以提高幼鼠的学习能力。
