Liebler Marko, Dreyer Thomas, Riedlinger Rainer E
Institut für Höchstfrequenztechnik und Elektronik/Akustik, Universität Karlsruhe, Kaiserstrasse 12, D-76128 Karlsruhe, Germany.
Ultrasonics. 2006 Dec 22;44 Suppl 1:e319-24. doi: 10.1016/j.ultras.2006.07.006. Epub 2006 Jul 31.
In medical applications of high intense focused ultrasound the mechanism of interaction between ultrasound waves and cavitation bubbles is responsible for several therapeutic effects as well as for undesired side effects. Based on a two-phase continuum approach for bubbly liquids, in this paper a numerical model is presented to simulate these interactions. The numerical results demonstrate the influence of the cavitation bubble cloud on ultrasound propagation. In the case of a lithotripter pulse an increased bubble density leads to significant changes in the tensile part of the pressure waveform. The calculations are verified by measurements with a fiber optical hydrophone and by experimental results of the bubble cloud dynamics.
在高强度聚焦超声的医学应用中，超声波与空化气泡之间的相互作用机制既产生了多种治疗效果，也带来了不良副作用。基于对含气泡液体的两相连续介质方法，本文提出了一个数值模型来模拟这些相互作用。数值结果表明了空化气泡云对超声传播的影响。在碎石脉冲的情况下，气泡密度增加会导致压力波形拉伸部分发生显著变化。通过光纤水听器测量以及气泡云动力学的实验结果对计算进行了验证。
