Zhang X-Q, Sun J-L, Ma R, Fan Z-Y, Dai Y, Sun J-Z
Department of General Surgery, General Hospital of Jinan Command, Shandong, China.
Transplant Proc. 2006 Jul-Aug;38(6):1840-1. doi: 10.1016/j.transproceed.2006.05.044.
Establish a simplified heterotopic small bowel transplantation (SBT) in the rat.
Ninety pairs of male Wistar rats were used as donors and recipients. The whole small intestine with a vascular pedicle composed of superior mesenteric artery (SMA) and portal vein (PV) was harvested as the graft. Revascularization was accomplished by end-to-side anastomosis between donor SMA and recipient infrarenal aorta and cuffed end-to-end anastomosis between donor PV and left renal vein of recipient. The distal end of graft was exteriorized to form an enterostoma.
Average time of an operation was 130 minutes and the mean warm ischemia time of grafts was 30 minutes. The technical success rate of this model was 100% and 7-day survival was 95.6% (86/90).
This simplified technique was effective and practical to improve the outcome of rat heterotopic SBT.
建立大鼠简化异位小肠移植（SBT）模型。
采用90对雄性Wistar大鼠作为供体和受体。切取带有由肠系膜上动脉（SMA）和门静脉（PV）组成的血管蒂的整个小肠作为移植物。通过供体SMA与受体肾下腹主动脉端侧吻合以及供体PV与受体左肾静脉套入端端吻合实现血管重建。将移植物远端外置形成肠造口。
平均手术时间为130分钟，移植物平均热缺血时间为30分钟。该模型的技术成功率为100%，7天存活率为95.6%（86/90）。
这种简化技术对于改善大鼠异位SBT的结果有效且实用。
