Kobayashi Junji, Murase Yuko, Asano Akimichi, Nohara Atsushi, Kawashiri Masa-aki, Inazu Akihiro, Yamagishi Masakazu, Mabuchi Hiroshi
Department of Lifestyle-related disease, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.
J Atheroscler Thromb. 2006 Aug;13(4):197-201. doi: 10.5551/jat.13.197.
To clarify the effects of walking with a pedometer on metabolic parameters, including adiponectin (APN).
We recruited 44 male Japanese volunteers (age, 37 +/- 9 yrs; body mass index (BMI), 24.2 +/- 2.9 kg/m2; fasting plasma glucose (FPG), 96 +/- 11 mg/dL; total cholesterol (TC) 190 +/- 26 mg/dL; triglycerides (TG) 119 +/- 80 mg/dL; HDL-C56 +/- 14 mg/dL). Subjects were instructed to walk with a pedometer and record the number of steps they walked every day for 50 days. Serum adiponectin (APN) levels were measured by enzyme immunoassay. Treatment effects were examined by Wilcoxon's rank test.
The average number of steps was 8211 +/- 2084 per day. There were significant reductions in BMI, sBP, TG and TNF-alpha levels after 50 days, but no changes in adiponectin levels. We then divided the subjects into 2 groups according to the steps walked per day, namely, more than 8000 steps (MT group, n = 22) and less than 8000 steps (LT group, n = 22) and found that the reduction in TG and BP was observed only in the MT group.
Walking with a pedometer is effective for improving metabolic parameters, such as TG and blood pressure, but is not sufficient to increase adiponectin levels in Japanese men.
阐明使用计步器步行对代谢参数的影响，包括脂联素（APN）。
我们招募了44名日本男性志愿者（年龄37±9岁；体重指数（BMI）24.2±2.9kg/m²；空腹血糖（FPG）96±11mg/dL；总胆固醇（TC）190±26mg/dL；甘油三酯（TG）119±80mg/dL；高密度脂蛋白胆固醇（HDL-C）56±14mg/dL）。受试者被要求使用计步器步行，并记录他们每天步行的步数，持续50天。通过酶免疫测定法测量血清脂联素（APN）水平。采用Wilcoxon秩和检验来检验治疗效果。
每天平均步数为8211±2084步。50天后，BMI、收缩压、TG和肿瘤坏死因子-α（TNF-α）水平显著降低，但脂联素水平没有变化。然后，我们根据每天步行的步数将受试者分为两组，即每天步数超过8000步（MT组，n = 22）和每天步数少于8000步（LT组，n = 22），发现只有MT组的TG和血压有所下降。
使用计步器步行对改善代谢参数（如TG和血压）有效，但不足以提高日本男性的脂联素水平。
