Weissenborn K, Scholz M, Hinrichs H, Wiltfang J, Schmidt F W, Künkel H
Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, F.R.G.
Electroencephalogr Clin Neurophysiol. 1990 Apr;75(4):289-95. doi: 10.1016/0013-4694(90)90107-u.
The spontaneous EEG, pattern reversal VEPs, and the P300 wave were studied in patients with liver cirrhosis and early stages of hepatic encephalopathy (HE). The sensitivities of the different neurophysiological methods in the early stages of hepatic encephalopathy were compared with each other and with several neuropsychological tests. P300 latency was shown to be the most appropriate neurophysiological method for detection of early HE. The diagnostic sensitivity of the P300 latency resembled that of the number connection test (NCT). These results are discussed with regard to methodological considerations and the clinical use of both methods.
对肝硬化和肝性脑病（HE）早期患者的自发脑电图、图形翻转视觉诱发电位（VEPs）和P300波进行了研究。将不同神经生理学方法在肝性脑病早期的敏感性相互比较，并与几种神经心理学测试进行比较。结果表明，P300潜伏期是检测早期肝性脑病最合适的神经生理学方法。P300潜伏期的诊断敏感性与数字连接试验（NCT）相似。就方法学考虑因素和这两种方法的临床应用对这些结果进行了讨论。
