Mullen Kevin D, Amodio Piero, Morgan Marsha Y
Department of Gastroenterology/Hepatology, MetroHealth Medical Center, Cleveland, OH, USA.
Metab Brain Dis. 2007 Dec;22(3-4):407-23. doi: 10.1007/s11011-007-9061-6.
This article has arisen from presentations made at the 4th International Hannover Conference on Hepatic Encephalopathy held in Dresden, 2006. Each author as listed describes their presentation given as part of a section entitled "Therapeutic Studies in Hepatic Encephalopathy." The first section deals with the justification for placebo-controlled trials in hepatic encephalopathy. The other two sections discuss, in detail, outcome parameters for therapeutic studies in the clinical and research setting, respectively.
本文源自2006年在德累斯顿举行的第四届汉诺威国际肝性脑病会议上的发言。文中列出的每位作者都描述了他们在题为“肝性脑病治疗研究”部分的发言。第一部分讨论了肝性脑病中安慰剂对照试验的合理性。另外两部分分别详细讨论了临床和研究环境中治疗研究的结果参数。