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健康人群中抗肠道病毒乳胶凝集抑制及中和抗体的持续性(作者译)

[Persistence of latex-agglutination inhibiting and neutralizing antibodies against enterovirus in the healthy population (author's transl)].

作者信息

Schmidt W A, Brade H, Klein M, Krämer U

出版信息

Dtsch Med Wochenschr. 1975 Aug 15;100(33):1663-6. doi: 10.1055/s-0028-1106440.

Abstract

Sera of 122 persons were examined by the neutralization and latex-agglutination inhibition tests for antibodies against Polio type I, Coxsackie virus type A 9 and B 4, as well as Echo virus type 9. With increasing age there was a titre difference between latex-agglutination inhibiting and neutralizing antibodies, due to the earlier fall in the former. These antibodies, contrary to neutralizing ones, were in the lower titre region. The results confirmed the usefulness of the latex-agglutination inhibition test in the diagnosis of acute enterovirus infections.

摘要

采用中和试验及乳胶凝集抑制试验检测了122人的血清,以检测其针对Ⅰ型脊髓灰质炎病毒、A9型和B4型柯萨奇病毒以及9型埃可病毒的抗体。随着年龄增长,乳胶凝集抑制抗体和中和抗体之间存在滴度差异,这是由于前者滴度下降更早。与中和抗体相反,这些抗体处于较低滴度范围。结果证实了乳胶凝集抑制试验在诊断急性肠道病毒感染中的实用性。

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