Williams Diane L, Goldstein Gerald, Minshew Nancy J
University of Pittsburgh School of Medicine, USA.
Child Neuropsychol. 2006 Aug;12(4-5):279-98. doi: 10.1080/09297040600681190.
A wide range of abilities was assessed in 56 high-functioning children with autism and 56 age- and IQ-matched controls. Stepwise discriminant analyses produced good group discrimination for sensory-perceptual, motor, complex language, and complex memory domains but lower agreement for the reasoning domain than previously obtained for adults. Group discrimination did not occur for attention, simple language, simple memory, and visuospatial domains. Findings provide additional support for a complex information-processing model for autism, previously based on adult data, demonstrating a pattern across domains of selective impairments on measures with high demands for integration of information and sparing when demands were low. Children as compared to adults with autism exhibited more prominent sensory-perceptual symptoms and less pronounced reasoning deficits reflecting brain maturation.
对56名高功能自闭症儿童和56名年龄及智商匹配的对照组儿童进行了广泛能力评估。逐步判别分析在感觉-知觉、运动、复杂语言和复杂记忆领域产生了良好的组间区分，但在推理领域的一致性低于之前对成年人的研究结果。在注意力、简单语言、简单记忆和视觉空间领域未出现组间区分。研究结果为先前基于成人数据的自闭症复杂信息处理模型提供了额外支持，表明在对信息整合要求高的测量中，各领域存在选择性损伤模式，而在要求低时则未受影响。与自闭症成年人相比，儿童表现出更明显的感觉-知觉症状和不太明显的推理缺陷，这反映了大脑的成熟。
