Walter T, Lebouche B, Miailhes P, Cotte L, Roure C, Schlienger I, Trepo C
Department of Hepatogastroenterology, Hospices Civils de Lyon, Hôtel-Dieu Hospital, Lyon,France.
Clin Infect Dis. 2006 Sep 15;43(6):787-90. doi: 10.1086/507099. Epub 2006 Aug 9.
We describe 3 symptomatic cases of neurologic syphilis that occurred after the administration of the usual therapy for primary or secondary syphilis in human immunodeficiency virus (HIV)-infected patients. We discuss the difficulty of diagnosing neurosyphilis, the need for lumbar puncture, and risk factors of relapse. Because HIV infection may alter the natural history and response of neurologic syphilis to treatment, scrupulous follow-up and repeated cycles of therapy are warranted.
我们描述了3例在对感染人类免疫缺陷病毒（HIV）的患者进行一期或二期梅毒常规治疗后发生的有症状神经梅毒病例。我们讨论了神经梅毒诊断的困难、腰椎穿刺的必要性以及复发的危险因素。由于HIV感染可能改变神经梅毒的自然病程和对治疗的反应，因此有必要进行严格的随访和重复治疗周期。
