Ricci Zaccaria, Ronco Claudio
Department of Pediatric Cardiosurgery, Bambino Gesù Hospital, Rome, Italy.
Crit Care. 2006;10(4):226. doi: 10.1186/cc4998.
We summarize original research in the field of critical care nephrology accepted or published in 2005 in Critical Care and, when considered relevant or directly linked to this research, in other journals. The articles have been grouped into four categories to facilitate a rapid overview. First, physiopathology, epidemiology and prognosis of acute renal failure (ARF): an extensive review and some observational studies have been performed with the aim of describing aspects of ARF physiopathology, precise epidemiology and long-term outcomes. Second, several authors have performed clinical trials utilizing a potential nephro-protective drug, fenoldopam, with different results. Third, the issue of continuous renal replacement therapies dose has been addressed in a small prospective study and a large observational trial. And fourth, alternative indications to extracorporeal treatment of ARF and systemic inflammatory response syndrome have been explored by three original clinical studies.
我们总结了2005年发表或被《重症监护》接受的重症监护肾脏病领域的原创研究，以及在其他期刊上发表的、与该研究相关或直接相关的研究。文章分为四类，以便快速浏览。第一，急性肾衰竭（ARF）的病理生理学、流行病学和预后：进行了广泛的综述和一些观察性研究，旨在描述ARF病理生理学、精确流行病学和长期预后的各个方面。第二，几位作者使用一种潜在的肾保护药物非诺多泮进行了临床试验，结果各异。第三，一项小型前瞻性研究和一项大型观察性试验探讨了持续肾脏替代疗法剂量的问题。第四，三项原创临床研究探索了ARF和全身炎症反应综合征体外治疗的替代适应症。
