Department of Pediatric Cardiosurgery, Bambino Gesù Hospital, Piazza S, Onofrio, 4 00165 Rome, Italy.
Crit Care. 2009;13(5):227. doi: 10.1186/cc7961. Epub 2009 Oct 21.
We summarize original research in the field of critical care nephrology accepted or published during 2008 in Critical Care and, when considered relevant or directly linked to this research, in other journals. Three main topics have been identified for a rapid overview. (1) The classification of acute kidney injury, with particular attention to differences and similarities between the RIFLE and AKIN classifications. (2) Fluid balance in patients requiring renal replacement therapy (RRT) has been shown as an independent risk factor for mortality in critically ill patients: current evidence and uncertainties are described. (3) Management of anticoagulation during RRT has been explored by several researchers in 2008: diagnosis of heparin-induced thrombocytopenia, the use of tirofiban and optimal anticoagulation during drotrecogin A activated treatment have been evaluated.
我们总结了 2008 年在《重症监护》和其他相关期刊上发表的重症监护肾脏病学领域的原始研究。为了快速概述，我们确定了三个主要主题。（1）急性肾损伤的分类，特别关注 RIFLE 和 AKIN 分类之间的差异和相似之处。（2）在需要肾脏替代治疗（RRT）的患者中，液体平衡已被证明是危重病患者死亡的独立危险因素：描述了当前的证据和不确定性。（3）2008 年，几位研究人员探讨了 RRT 期间的抗凝管理：肝素诱导的血小板减少症的诊断、替罗非班的使用以及在激活治疗中使用 drotrecogin A 时的最佳抗凝。
