Marsden C D, Sheehy M P
University Department of Clinical Neurology, National Hospital for Nervous Diseases, Queen Square, London, UK.
Trends Neurosci. 1990 Apr;13(4):148-53. doi: 10.1016/0166-2236(90)90007-w.
Writer's cramp has been recognized for over a century, and originally was construed as a physical motor disorder. However, an unfortunate use of the descriptive term 'professional neuroses' to describe this and other similar task-specific conditions, coupled subsequently with fashions in psychiatry, led to the mistaken belief that writer's cramp was due to psychic rather than motor pathology. Evidence has accumulated in recent years showing that writer's cramp is a real focal motor disorder, with a close relation to dystonia. This article summarizes what is known about the aetiology, clinical features, pathophysiology and treatment of writer's cramp and analogous occupational cramps, with the aim of drawing the attention of neuroscientists to this common, bizarre and poorly understood condition.
书写痉挛已被认识一个多世纪了,最初它被视为一种躯体运动障碍。然而,不幸的是,人们用“职业神经症”这一描述性术语来形容这种及其他类似的特定任务相关病症,随后又受到精神病学潮流的影响,导致人们错误地认为书写痉挛是由精神而非运动病理学引起的。近年来积累的证据表明,书写痉挛是一种真正的局灶性运动障碍,与肌张力障碍密切相关。本文总结了关于书写痉挛及类似职业性痉挛的病因、临床特征、病理生理学和治疗方面的已知情况,旨在引起神经科学家对这种常见、奇特且了解甚少的病症的关注。