Kristeva R, Cheyne D, Lang W, Lindinger G, Deecke L
Neurological University Clinic, Vienna, Austria.
Electroencephalogr Clin Neurophysiol. 1990 May;75(5):410-8. doi: 10.1016/0013-4694(90)90086-y.
The present study was aimed at investigating the effect of inertial loading on movement-related potentials (MRPs) recorded from the scalps of normal subjects while performing finger movements. Two experiments were performed. Experiment 1. MRPs preceding and accompanying the execution of voluntary, unilateral finger movements were investigated in 8 subjects under the 3 experimental conditions of: no inertial load, small inertial load (250 g), and large inertial load (400 g). A significant effect of the inertial load on Bereitschaftspotential (BP) amplitude was observed for the 100 msec period preceding movement onset (BP -100 to 0) at precentral electrode sites and following movement onset (N0 to 100) at both precentral and parietal electrode sites. Pairwise comparisons revealed that significant effects were due to differences between the loading and non-loading conditions and not for different amounts of loading. No significant differences were observed for BP onset or early BP amplitudes, indicating that scalp negativity immediately prior to, and during, movement onset is primarily influenced by conditions of inertial loading. Experiment 2. This experiment examined the effect of inertial loading on MRPs for bilateral, simultaneous voluntary finger movements in 10 subjects under conditions of: no inertial load, inertial load applied separately to the left and right fingers, and with identical inertial loads applied to both fingers. No significant effect of inertial load on MRP amplitude was observed. These results are contrasted with those of experiment 1 which show significant effects of inertial loading for unilateral movements and are interpreted in terms of the hypothesis that bilateral movement organization involves 'higher' aspects of motor control than those reflecting adjustment to conditions of inertial loading.
本研究旨在调查惯性负荷对正常受试者在进行手指运动时头皮记录的运动相关电位（MRP）的影响。进行了两项实验。实验1：在8名受试者中，于无惯性负荷、小惯性负荷（250克）和大惯性负荷（400克）这3种实验条件下，研究了自愿单侧手指运动执行前及执行过程中的MRP。在运动开始前100毫秒期间（BP -100至0），在中央前回电极部位，以及运动开始后（N0至100），在中央前回和顶叶电极部位，均观察到惯性负荷对 Bereitschaftspotential（BP）振幅有显著影响。两两比较显示，显著影响是由于负荷与无负荷条件之间的差异，而非不同负荷量之间的差异。未观察到BP起始或早期BP振幅有显著差异，这表明运动开始前及运动过程中的头皮负电位主要受惯性负荷条件影响。实验2：本实验在10名受试者中，于无惯性负荷、分别对左右手指施加惯性负荷以及对双手手指施加相同惯性负荷的条件下，研究了惯性负荷对双侧同时自愿手指运动的MRP的影响。未观察到惯性负荷对MRP振幅有显著影响。这些结果与实验1的结果形成对比，实验1显示惯性负荷对单侧运动有显著影响，这些结果根据以下假设进行解释：双侧运动组织涉及比反映对惯性负荷条件调整的那些方面“更高”层次的运动控制。
