Kristeva R, Keller E, Deecke L, Kornhuber H H
Abteilung Neurologie, Universität Ulm, G.F.R.
Electroencephalogr Clin Neurophysiol. 1979 Aug;47(2):229-38. doi: 10.1016/0013-4694(79)90223-2.
Cerebral potentials preceding voluntary bilateral simultaneous finger movements were investigated in 19 right-handed young adult subjects, and were compared with unilateral right-sided finger m n the same experiment. With bilateral movements, the Bereitschaftspotential (BP) was not symmetrical or larger over the dominant hemisphere, but surprisingly, it was larger over the minor hemisphere. The BP averaged -3.66 microV (S.D. 1.96) over the left precentral region and -4.82 microV (S.D. 3.73) over the right precentral region in this condition. The difference was significant at 2P less than 0.01. This difference was pronounced in precentral leads but very small and almost missing in parietal leads. The pre-motion positivity (PMP) was well developed and even larger with bilateral than with unilateral (right-sides) movements. At the vertex it averaged +1.33 microV (S.D.4.16) with bilateral movements and only +0.15 microV (S.D. 1.42) with right-sided unilateral movements (2P less than 0.05). With bilateral movements the PMP could be observed in any record, but with unilateral movements it was missing at the left precentral lead, in accordance with previous publications (Deecke et al. 1969, 1976). The motor potential (MP), measured in a bipolar record from left and right precentral leads, was larger with unilateral (-1.25 microV, S.D. 1.33) than with bilateral movements (-0.36 microV, S.D. 0.92). Onset time differences of the BP preceding unilateral and bilateral movements were very small. However, there was a tendency towards earlier onset with unilateral than with bilateral movements (1031 msec, S.D. 358, as compared with 951 msec, S.D. 305). The averaged EMG revealed differences in movement onset. Muscular contraction tended to be earlier in the right than in the left m. flexor indicis in our right-handed subjects, on the average by 16 msec (S.D. 15). With unilateral right-sided movements, the left m. flexor indicis was not silent but showed an abortive mirror activity in the EMG, without visible movement. This activity occurred on the average 50 msec (S.D. 39) later on the non-moving side.
在19名右利手的年轻成年受试者中，研究了双侧同时进行随意手指运动之前的脑电位，并在同一实验中将其与右侧单侧手指运动的情况进行了比较。在双侧运动时，准备电位（BP）在优势半球上并非对称或更大，令人惊讶的是，它在非优势半球上更大。在此条件下，左侧中央前回区域的BP平均为-3.66微伏（标准差1.96），右侧中央前回区域的BP平均为-4.82微伏（标准差3.73）。这种差异在P值小于0.01时具有显著性。这种差异在中央前回导联中很明显，但在顶叶导联中非常小，几乎不存在。运动前正波（PMP）发展良好，双侧运动时甚至比单侧（右侧）运动时更大。在头顶，双侧运动时其平均为+1.33微伏（标准差4.16），右侧单侧运动时仅为+0.15微伏（标准差1.42）（P值小于0.05）。在双侧运动时，任何记录中都可观察到PMP，但在单侧运动时，根据先前的研究（德克等人，1969年、1976年），左侧中央前回导联中未出现PMP。从左侧和右侧中央前回导联的双极记录中测量的运动电位（MP），单侧运动时（-1.25微伏，标准差1.33）比双侧运动时（-0.36微伏，标准差0.92）更大。单侧和双侧运动之前BP的起始时间差异非常小。然而，存在单侧运动比双侧运动起始更早的趋势（单侧运动为1031毫秒，标准差358，双侧运动为951毫秒，标准差305）。平均肌电图显示运动起始存在差异。在我们的右利手受试者中，右侧屈指肌的肌肉收缩往往比左侧更早，平均早16毫秒（标准差15）。在右侧单侧运动时，左侧屈指肌并非静止不动，而是在肌电图中显示出一种未成功的镜像活动，没有可见的运动。这种活动在非运动侧平均比运动侧晚50毫秒（标准差39）出现。
