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J Bacteriol. 2006 Aug;188(16):5878-87. doi: 10.1128/JB.00486-06.
2
Response of Bacillus subtilis to nitric oxide and the nitrosating agent sodium nitroprusside.枯草芽孢杆菌对一氧化氮和亚硝化剂硝普钠的反应。
J Bacteriol. 2004 Jul;186(14):4655-64. doi: 10.1128/JB.186.14.4655-4664.2004.
3
Flavohemoglobin denitrosylase catalyzes the reaction of a nitroxyl equivalent with molecular oxygen.黄素血红蛋白去亚硝化酶催化一个硝酰基等价物与分子氧的反应。
Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10108-12. doi: 10.1073/pnas.181199698. Epub 2001 Aug 21.
4
Interaction of ResD with regulatory regions of anaerobically induced genes in Bacillus subtilis.枯草芽孢杆菌中ResD与厌氧诱导基因调控区域的相互作用。
Mol Microbiol. 2000 Sep;37(5):1198-207. doi: 10.1046/j.1365-2958.2000.02075.x.
5
Nitric-oxide dioxygenase activity and function of flavohemoglobins. sensitivity to nitric oxide and carbon monoxide inhibition.黄素血红蛋白的一氧化氮双加氧酶活性与功能。对一氧化氮和一氧化碳抑制的敏感性。
J Biol Chem. 2000 Oct 13;275(41):31581-7. doi: 10.1074/jbc.M004141200.
6
New functions for the ancient globin family: bacterial responses to nitric oxide and nitrosative stress.古老珠蛋白家族的新功能:细菌对一氧化氮和亚硝化应激的反应
Mol Microbiol. 2000 May;36(4):775-83. doi: 10.1046/j.1365-2958.2000.01889.x.
7
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Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4672-6. doi: 10.1073/pnas.090083597.
8
The flavohemoglobin of Escherichia coli confers resistance to a nitrosating agent, a "Nitric oxide Releaser," and paraquat and is essential for transcriptional responses to oxidative stress.大肠杆菌的黄素血红蛋白赋予其对亚硝化剂、“一氧化氮释放剂”和百草枯的抗性,并且对于氧化应激的转录反应至关重要。
J Biol Chem. 1999 Jan 8;274(2):748-54. doi: 10.1074/jbc.274.2.748.
9
Nitrosative stress: metabolic pathway involving the flavohemoglobin.亚硝化应激:涉及黄素血红蛋白的代谢途径。
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14100-5. doi: 10.1073/pnas.95.24.14100.
10
Nitric oxide dioxygenase: an enzymic function for flavohemoglobin.一氧化氮双加氧酶:黄素血红蛋白的一种酶功能。
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黄素血红蛋白在枯草芽孢杆菌长期厌氧存活中的关键作用。

Essential role of flavohemoglobin in long-term anaerobic survival of Bacillus subtilis.

作者信息

Nakano Michiko M

机构信息

Department of Environmental and Biomolecular Systems, OGI School of Science and Engineering, Oregon Health and Science University, 20000 NW Walker Road, Beaverton, OR 97006, USA.

出版信息

J Bacteriol. 2006 Sep;188(17):6415-8. doi: 10.1128/JB.00557-06.

DOI:10.1128/JB.00557-06
PMID:16923910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1595361/
Abstract

A Bacillus subtilis culture incubated anaerobically in nitrate-containing medium lost viability during the first 3 days but recovered thereafter. A flavohemoglobin mutant showed very poor survival under these conditions unless the cells were prevented from carrying out nitrate respiration.

摘要

在含硝酸盐的培养基中厌氧培养的枯草芽孢杆菌培养物在最初3天内失去活力,但此后恢复。一种黄素血红蛋白突变体在这些条件下存活率极低,除非阻止细胞进行硝酸盐呼吸。