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球壳菌素A，一种从内生真菌中分离出的STAT3依赖性信号传导抑制剂。

Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus.

作者信息

Maloney Katherine N, Hao Wenshan, Xu Jun, Gibbons Jay, Hucul John, Roll Deborah, Brady Sean F, Schroeder Frank C, Clardy Jon

机构信息

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

出版信息

Org Lett. 2006 Aug 31;8(18):4067-70. doi: 10.1021/ol061556f.

DOI:10.1021/ol061556f
PMID:16928075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2518690/
Abstract

Phaeosphaeride A, a nitrogen-containing bicyclic compound produced by an endophytic fungus, inhibits signaling by the transcription factor STAT3.

摘要

球孢壳菌素A是一种由内生真菌产生的含氮双环化合物，可抑制转录因子STAT3的信号传导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/777a/2518690/46c4aa0e0f71/nihms-61224-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/777a/2518690/46c4aa0e0f71/nihms-61224-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/777a/2518690/46c4aa0e0f71/nihms-61224-f0001.jpg

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