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冠状动脉搭桥手术候选者的认知功能

Cognitive function in candidates for coronary artery bypass graft surgery.

作者信息

Ernest Christine S, Murphy Barbara M, Worcester Marian U C, Higgins Rosemary O, Elliott Peter C, Goble Alan J, Le Grande Michael R, Genardini Natalie, Tatoulis James

机构信息

Heart Research Centre, Royal Melbourne Hospital, Victoria, Australia.

出版信息

Ann Thorac Surg. 2006 Sep;82(3):812-8. doi: 10.1016/j.athoracsur.2006.04.005.

DOI:10.1016/j.athoracsur.2006.04.005
PMID:16928490
Abstract

BACKGROUND

While many studies have investigated cognitive impairments in patients after coronary artery bypass graft surgery, very few have closely evaluated presurgical cognitive functioning of bypass candidates.

METHODS

A battery of neuropsychologic tests was administered to a consecutive series of patients listed for bypass surgery (n = 109). Cognitive function of bypass candidates was compared with that of a healthy control group (n = 25) and published test norms.

RESULTS

Cognitive test scores in candidates for bypass were significantly lower than those of the control group on tests of attention, information processing speed, and verbal memory. Additionally, bypass candidates' cognitive test scores were significantly reduced compared with expected values derived from validated test norms, on all but one cognitive test.

CONCLUSIONS

Cognitive performances of candidates for bypass were significantly lower than those of a healthy control group and published cognitive test norms.

摘要

背景

虽然许多研究调查了冠状动脉搭桥手术后患者的认知障碍,但很少有研究密切评估搭桥手术候选人术前的认知功能。

方法

对一系列连续的等待搭桥手术的患者(n = 109)进行了一组神经心理学测试。将搭桥手术候选人的认知功能与健康对照组(n = 25)以及已发表的测试常模进行比较。

结果

在注意力、信息处理速度和言语记忆测试中,搭桥手术候选人的认知测试分数显著低于对照组。此外,除一项认知测试外,与从经过验证的测试常模得出的预期值相比,搭桥手术候选人的认知测试分数显著降低。

结论

搭桥手术候选人的认知表现显著低于健康对照组以及已发表的认知测试常模。

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