接受冠状动脉造影术患者的认知功能
Cognitive function in patients undergoing coronary angiography.
作者信息
Devapalasundarum A N, Silbert B S, Evered L A, Scott D A, MacIsaac A I, Maruff P T
机构信息
Centre for Anaesthesia and Cognitive Function, Department of Anaesthesia, St Vincent's Hospital, Melbourne, Australia.
Centre for Anaesthesia and Cognitive Function, Department of Anaesthesia, St Vincent's Hospital, Melbourne, Australia; Department of Surgery, St Vincent's Hospital, University of Melbourne, Melbourne, Australia.
出版信息
Heart Asia. 2010 Jul 29;2(1):75-9. doi: 10.1136/ha.2009.001230. eCollection 2010.
OBJECTIVE
To measure cognition in patients before and after coronary angiography.
DESIGN
Prospective observational cohort study.
SETTING
University teaching hospital.
PATIENTS
56 patients presenting for elective coronary angiography.
MAIN OUTCOME MEASURES
Computerised cognitive test battery administered before coronary angiography, before discharge from hospital and 7 days after discharge. A matched healthy control group was used as a comparator.
RESULTS
When analysed by group, coronary angiography patients performed worse than matched controls at each time point. When the cognitive change was examined for each individual, of the 48 patients tested at discharge, 19 (39.6%) were classified as having a new cognitive dysfunction, and of 49 patients tested at day 7, six (12.2%) were classified as having a new cognitive dysfunction.
CONCLUSIONS
The results confirm that cognitive function is decreased in patients who have cardiovascular disease. Furthermore, coronary angiography may exacerbate this impaired cognition in some patients.
目的
测量冠状动脉造影术前及术后患者的认知情况。
设计
前瞻性观察队列研究。
地点
大学教学医院。
患者
56例接受择期冠状动脉造影的患者。
主要观察指标
在冠状动脉造影术前、出院前及出院后7天进行计算机化认知测试组。选取匹配的健康对照组作为对照。
结果
按组分析时，冠状动脉造影患者在每个时间点的表现均比匹配对照组差。对每个个体的认知变化进行检查时，在出院时接受测试的48例患者中，19例（39.6%）被归类为有新的认知功能障碍，在第7天接受测试的49例患者中，6例（12.2%）被归类为有新的认知功能障碍。
结论
结果证实心血管疾病患者的认知功能会下降。此外，冠状动脉造影可能会使部分患者受损的认知进一步恶化。
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