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在尼日利亚阿布贾一家指定的艾滋病毒治疗与护理中心就诊的成年艾滋病毒血清阳性患者中卡波西肉瘤的患病率。

Prevalence of Kaposi's sarcoma among adult HIV-seropositive patients seen in a designated HIV treatment and care center in Abuja, Nigeria.

作者信息

Iregbu K C, Elegba O Y

机构信息

Department of Clinical Microbiology and Parasitology, National Hospital, P.M.B. 425 Garki, Abuja, Nigeria.

出版信息

J Int Assoc Physicians AIDS Care (Chic). 2006 Sep;5(3):115-8. doi: 10.1177/1545109706290176.

Abstract

BACKGROUND

There is a dearth of information on the prevalence of AIDS-associated Kaposi's sarcoma (AAKS) in Nigeria despite the HIV National seroprevalence of 5% and the occurrence of the disease in people living with HIV/AIDS.

OBJECTIVE

To determine the prevalence of AAKS among HIV-seropositive adults seen in an HIV/AIDS treatment and care center in Abuja, Nigeria.

DESIGN

This was a retrospective study of all cases seen over a period of 42 months.

METHOD

Medical records of the 1591 patients comprising 857 males and 734 females were reviewed, and relevant data such as age, sex, CD4 count at diagnosis of AAKS were obtained and analyzed.

RESULTS

A prevalence of 0.8% was found, with a male:female ratio of 2:1. Females presented at earlier ages and relatively lower CD4 count than did males.

CONCLUSION

Easy access to antiretroviral medications and a well-targeted education and awareness campaign will help reduce the incidence and prevalence of the disease. The inability to perform histologic examinations on all suspected cases calls for a well-designed prospective study to determine the actual prevalence of Kaposi's sarcoma in HIV-seropositive patients in Nigeria.

摘要

背景

尽管尼日利亚全国艾滋病毒血清流行率为5%,且艾滋病病毒/艾滋病感染者中出现了这种疾病,但关于艾滋病相关卡波西肉瘤(AAKS)患病率的信息却很匮乏。

目的

确定在尼日利亚阿布贾一家艾滋病毒/艾滋病治疗与护理中心就诊的艾滋病毒血清阳性成年人中AAKS的患病率。

设计

这是一项对42个月期间所有病例的回顾性研究。

方法

对1591例患者(包括857名男性和734名女性)的病历进行了审查,并获取和分析了相关数据,如年龄、性别、诊断AAKS时的CD4细胞计数。

结果

发现患病率为0.8%,男女比例为2:1。女性发病年龄较早,CD4细胞计数相对低于男性。

结论

方便获得抗逆转录病毒药物以及开展针对性强的教育和宣传活动将有助于降低该疾病的发病率和患病率。无法对所有疑似病例进行组织学检查,因此需要开展精心设计的前瞻性研究,以确定尼日利亚艾滋病毒血清阳性患者中卡波西肉瘤的实际患病率。

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