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心脏大手术后的术后感染及呼吸机相关性肺炎的预防:一项欧洲单日患病率研究(ESGNI-008)

Postoperative infections after major heart surgery and prevention of ventilator-associated pneumonia: a one-day European prevalence study (ESGNI-008).

作者信息

Bouza E, Hortal J, Muñoz P, Pascau J, Pérez M J, Hiesmayr M

机构信息

Servicio de Microbiología Clínica y Enfermedades Infecciosas-VIH, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

出版信息

J Hosp Infect. 2006 Nov;64(3):224-30. doi: 10.1016/j.jhin.2006.06.019. Epub 2006 Aug 22.

Abstract

Few data have been published on the prevalence of postoperative infection in patients undergoing major heart surgery (MHS). The degree of compliance with standard measures used to prevent them is unknown. This study assessed the prevalence of infections, particularly ventilator-associated pneumonia (VAP), in patients undergoing MHS in 42 institutions from 13 European countries. On the study day, there were 321 postoperative MHS patients, of whom 164 (51%) were mechanically ventilated. The overall prevalence of infection was 26.8%. Lower respiratory tract infections represented 57% of all the infections present on the study day. Other infections included intravenous-catheter-related bloodstream infections (2.8%), surgical site infections (2.2%), urinary tract infections (0.9%) and postoperative mediastinitis (0.9%). Of the mechanically ventilated patients, 55 (33.5%) were not being nursed in a semi-recumbent position, 36 (22%) had heat-moisture exchangers with no antibacterial filters, and intracuff pressure was not monitored in 78 patients (47.6%). Only 13 patients (8%) were given continuous subglottic suctioning, 64 patients (39%) did not receive postural oscillation, and gastric overdistension was not actively prevented in 23 patients (14%). In conclusion, these data from intensive care units across Europe provide information on postoperative infections in an important subset of the patient population, and stress the need for active interventions to prevent VAP in patients undergoing MHS.

摘要

关于接受心脏大手术(MHS)患者术后感染的患病率,已发表的数据很少。用于预防感染的标准措施的依从程度尚不清楚。本研究评估了来自13个欧洲国家42家机构中接受MHS患者的感染患病率,尤其是呼吸机相关性肺炎(VAP)。在研究当日,有321例MHS术后患者,其中164例(51%)接受机械通气。感染的总体患病率为26.8%。下呼吸道感染占研究当日所有感染的57%。其他感染包括静脉导管相关血流感染(2.8%)、手术部位感染(2.2%)、尿路感染(0.9%)和术后纵隔炎(0.9%)。在接受机械通气的患者中,55例(33.5%)未采用半卧位护理,36例(22%)使用无抗菌过滤器的热湿交换器,78例患者(47.6%)未监测气管套囊内压力。只有13例患者(8%)接受持续声门下吸引,64例患者(39%)未接受体位振荡,23例患者(14%)未积极预防胃过度扩张。总之,来自欧洲各地重症监护病房的数据提供了关于这一重要患者亚群术后感染的信息,并强调了对接受MHS患者预防VAP进行积极干预的必要性。

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