Yoshida Kazuya, Iizuka Tadahiko
Dept. of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.
Cranio. 2006 Jul;24(3):217-22. doi: 10.1179/crn.2006.035.
To examine the effects of botulinum toxin injection application for the treatment of upper airway obstruction due to hyperactive lateral pterygoid muscle contraction, we applied botulinum toxin injection. A 20 year-old male patient had involuntary mouth opening after a diabetic coma. His mouth opened excessively (84 mm) particularly when he was in a nervous or stressed condition. This resulted in a bilateral temporomandibular dislocation and, consequently, upper airway collapse. The differential diagnosis of jaw-opening oromandibular dystonia was made. Botulinum toxin type A was bilaterally injected into the lateral pterygoid muscle. The excessive mouth opening was reduced, and the patient showed no temporomandibular joint (TMJ) dislocation or experienced any further airway collapse after the injections. We successfully applied botulinum toxin to a patient with upper airway obstruction and TMJ dislocation relative to jaw-opening dystonia.
为研究肉毒杆菌毒素注射治疗因翼外肌过度收缩导致的上气道阻塞的效果,我们进行了肉毒杆菌毒素注射。一名20岁男性患者在糖尿病昏迷后出现不自主张口。他的嘴巴过度张开(84毫米),尤其是在紧张或有压力的情况下。这导致了双侧颞下颌关节脱位,进而导致上气道塌陷。做出了张口型口下颌肌张力障碍的鉴别诊断。将A型肉毒杆菌毒素双侧注射到翼外肌中。过度张口得到缓解,注射后患者未出现颞下颌关节(TMJ)脱位,也未发生进一步的气道塌陷。我们成功地将肉毒杆菌毒素应用于一名因张口型肌张力障碍导致上气道阻塞和TMJ脱位的患者。