Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Magn Reson Chem. 2010 May;48(5):392-6. doi: 10.1002/mrc.2582.
The chemical study of Momordica charantia fruits led to the isolation of three new cucurbitane triterpene glycosides, momordicosides U, V, and W (1-3). The structures of these compounds were determined to be (19R, 23R)-5beta, 19-epoxy-19-methoxycucurbita-6,24-diene-3beta, 23-diol 3-O-beta-D-allopyranoside (1), (23R)-5beta, 19-epoxycucurbita-6,24-diene-3beta, 23-diol 3-O-beta-D-allopyranoside (2), and (19R)-5beta, 19-epoxy-19,25-dihydroxycucurbita-6,23(E)-diene-3beta-ol 3-O-beta-D-glucopyranoside (3), by chemical and spectroscopic methods.
苦瓜果实的化学研究导致了三种新的葫芦烷三萜糖苷的分离，分别是苦瓜甙 U、V 和 W（1-3）。这些化合物的结构被确定为（19R，23R）-5β，19-环氧-19-甲氧基葫芦烷-6，24-二烯-3β，23-二醇 3-O-β-D-吡喃阿洛糖苷（1），（23R）-5β，19-环氧葫芦烷-6，24-二烯-3β，23-二醇 3-O-β-D-吡喃阿洛糖苷（2）和（19R）-5β，19-环氧-19，25-二羟基葫芦烷-6，23（E）-二烯-3β-醇 3-O-β-D-吡喃葡萄糖苷（3），通过化学和光谱方法。
